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    Effect of propolis on wound healing in sacrococcygeal pilonidal disease: A randomized controlled clinical trial
    (Univ Karachi, 2021) Kubat, Mehmet; Karabulut, Zulfikar; Sengul, Serkan
    Wound healing and recurrence are the leading problems encountered in sacrococcygeal pilonidal sinus disease. Propolis has a place in both traditional and complementary medicine, and in vitro and in vivo studies have reported its anti-inflammatory, anti-oxidant, anti-bacterial, anti-fungal and immunostimulant properties. In the present study, we discuss the effect of propolis on wound healing in sacrococcygeal pilonidal diseases treated with marsupialization. Patients who were admitted to our clinic with sacrococcygeal pilonidal disease were analyzed prospectively, with a total of 33 patients divided into study and control groups. All patients underwent marsupialization surgery, and the wound areas were analyzed post-operatively, on the 0, 7th, 14th, 28th days and on the day of complete recovery. An acceleration of wound healing was observed from the first week that was found to be even faster between days 14 and 28. The complete recovery score in the study group was significantly lower. Propolis can be used to accelerate wound healing when the marsupialization method is preferred in patients diagnosed with uncomplicated sacrococcygeal pilonidal cyst due to its low cost, good patient compliance, low side effect profile, lack of toxicity and high efficacy.
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    Öğe
    When Should Definitive Surgery Be Performed After Sacrococcygeal Pilonidal Sinus Abscess Drainage
    (2023) Güler, Yılmaz; Sengul, Serkan; Çalış, Hasan; Karabulut, Zulfikar; Ozen, Ozkan
    Objective: The abscess development is one of the common clinical presentations of pilonidal sinus. Treatment in pilonidal sinus abscesses involves allowing secondary recovery following wide local excision with drainage, and excision procedures are performed after a few weeks and after the infection is completely cured. We aimed to investigate the effect of the time interval between the abscess drainage and definitive surgical treatment on the development of postoperative complications in patients who had pilonidal sinus abscess. Methods: The patients were divided into 2 groups according to the time interval from abscess drainage to sinus excision surgery: patients who under- went sinus excision 1 month after abscess drainage comprised group 1 and patients who underwent sinus excision 3 months after abscess drainage comprised group 2. Sinus excision and primary closure surgery were performed in patients in both groups. Results: In total, 44 patients (53.0%) underwent sinus excision group 1 and 39 patients (47.0%) underwent sinus excision group 2 after abscess drainage. Postoperative wound infection and wound dehiscence rates were significantly higher in group 1 patients than in group 2 patients (P < .05). Conclusion: We suggest that for reducing postoperative complications, it would be a better approach performing sinus excision after waiting for at least 3 months following drainage instead of performing excision right after recovery of infection or within a few weeks after the abscess drainage.