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    A bibliometric analysis of the literature from the past to the present on the use of artificial intelligence in orthodontics and orthognathic surgery
    (2025) Gülşen, İbrahim Tevfik; Erdem, Ruşen; Genç, Yavuz Selim; Gülşen, Emine
    Aims: This study aims to investigate the publication characteristics of academic work centred around artificial intelligence (AI) in orthodontics and orthognathic surgery in detail. Methods: In this analysis, the VOSviewer software and the Bibliometrix Biblioshiny R-package were employed for the purposes of bibliometric investigation and data visualisation. Results: Between 1991 and 2024, 842 articles were published, averaging 12.33 citations per article. China topped the list with 200 articles, succeeded by the U.S. with 183 and South Korea with 121. Seoul National University authored the highest number of publications (47), succeeded by Peking University (36) and the University of North Carolina (34). Seoul National University (807) and the Catholic University of Leuven (567) ranked highest in citation impact. Jacobs Reinhilde was the most prolific author, with 22 publications, and alongside Dinggang Shen and Adriaan Van Gerven, had the greatest citation counts of 544, 491, and 476, respectively. The most used keywords were “artificial intelligence,” “deep learning,” “machine learning,” “orthodontics,” “convolutional neural network,” “orthognathic surgery,” “dentistry,” “cephalometry,” “CBCT,” and “cephalometric analysis.” Conclusion: This bibliometric analysis illustrates that AI has swiftly become an expanding research subject in orthodontics and orthognathic surgery, attracting considerable interest from the scientific community. The thorough investigation indicates that AI is essential, especially in cephalometric evaluations, diagnostic procedures, and treatment strategies.
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    Clinical management of epidermolysis bullosa: case reports of five siblings
    (Endo Press LLC, 2025) Gülşen, Emine; Sariyldiz, Cansu Osmanoğullari; Gülşen, İbrahim Tevfik; Maharani, Diah Ayu; Goncharuk-Khomyn, Myroslav Yu; Yavuz, I.; Callea, M.
    INTRODUCTION. Epidermolysis bullosa (EB) is a rare, inherited disorder characterized by mucocutaneous fragility, leading to blistering and ulceration following minimal trauma. Among its major subtypes, EB simplex (EBS) is the most common, typically presenting with milder clinical manifestations. AIM. This case series aims to document the clinical and radiographic findings of five siblings diagnosed with EBS, emphasizing the role of dental professionals in diagnosis, management, and improving patient quality of life. MATERIALS AND METHODS. Five siblings with no prior EB diagnosis underwent clinical, radiographic, and genetic assessments. Intraoral and extraoral examinations were conducted to evaluate mucosal involvement, dental anomalies, and associated systemic manifestations. Genetic analysis confirmed EBS Type 2 (KRT5 mutation) in all cases. RESULTS. None of the cases exhibited significant oral mucosal bullae or erosions. However, hyperkeratotic lesions, nail dystrophy, and perioral bullous formations were observed in all patients. Two siblings presented with bilateral sensorineural hearing loss. Panoramic radiographs revealed missing teeth, likely due to cariesrelated extractions, highlighting challenges in oral hygiene maintenance. Dental management focused on atraumatic treatment approaches, preventive care, and dietary counseling. CONCLUSIONS. Dentists play a crucial role in the early detection and multidisciplinary management of EB. Comprehensive oral assessments can aid in subtype identification and guide tailored treatment strategies. Patient education, preventive measures, and regular follow-ups are essential to improving long-term oral health outcomes and overall quality of life for individuals with EB. © Gülşen E., Sariyldiz C.O., Gülşen İ.T., Maharani D.A., Goncharuk-Khomyn M., Yavuz İ., Callea M., Yavuz C., 2025.