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    Analysis of traumatic bone cyst of the jaws: A retrospective study
    (2019) Demirbaş, Ahmet Emin; Çolpak, Halis Ali; Kütük, Nükhet; Gönen, Zeynep Burçin; Alkan, Alper
    Objective: Traumatic bone cysts (TBC) are rare in the jaws, and may be characterized by the presence of a cavity in bone with no epithelial lining. Clinically, TBC is asymptomatic and often discovered incidentally on routine radiographic examination. The purpose of this study was to describe the clinical, surgical, and radiographic features of TBCs.Materials and Methods: Records of patients with cystic lesions, who were treated in our clinic between 2006 and 2016, were examined. Twenty-two TBCs were detected among all odontogenic/nonodontogenic cysts. Clinical, radiographical, histopathological features of TBCs and follow-up information of the patients were analyzed retrospectively.Results: The mean age of the patients was 18.5. The incidence of the TBC was found 1.05%. All lesions were found in the mandible, and were diagnosed incidentally during routine dental examinations except two cases have pain. Most cases showed a cavity without an epithelial lining, and were treated with curettage. No complications occurred during follow up period.Conclusion: TBCs are rare seen in the jaws, and the mandible is generally affected site. Bone healing may be accomplished successfully with the curettage of the cyst cavity.
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    Effects of bisphosphonate treatment on mandibular condyle tissues of temporomandibular joint: A stereological study
    (Elsevier, 2019) Gönen, Zeynep Burçin; Çolpak, Halis Ali; Önger, Mehmet Emin
    Introduction: Although the adverse effects due to the use of bisphosphonates, such as bisphosphonate-induced osteonecrosis of the jaw, are reported previously, whether adverse events of the temporomandibular joint related with bisphosphonate treatment have been still unclear. Therefore, the aim of this study is to evaluate the effects of BP treatment on the condylar tissues of the temporomandibular joint due to fibrous cartilage, hyaline cartilage and bone-specific differences in rat animal models. Material and method: A total of 12 adult Wistar-Albino rats, weighing from 250 to 300 g were included to the study. The animals were randomly divided into two groups. 0.1 mg/kg Zoledronic Acid were administrated to the animals intraperitoneally in the experimental bisphosphonate group for 60 days. Rest of the animals left as healthy control. All the animals were sacrificed at the end of 60 days. Two condyles were obtained from each animal and total 12 condyles were included to histological analysis in each group. The fibrous cartilage volume, hyaline cartilage volume and bone volume of the condyle were calculated using Cavalieri method. Statistical analysis was performed with Turcosa software. Results: There is a statistically significant difference of fibrous cartilage (P = 0.003) and bone volume between groups (P = 0.002). However, mean hyaline cartilage volume does not statistically differ between groups (P = 0.47). Bone volume and firbrous cartilage volume were increased in bisphosphonate group than control. Conclusion: According to our study results Zoledronic Acid treatment did not affect the hyaline cartilage volume however fibrocartilage volume and bone volume were increased when the animals received ZA intraperitoneally for 60 days. (C) 2019 Published by Elsevier Masson SAS.