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    A RARE ENTITY OF ACQUIRED IDIOPATHIC GENERALISED ANHIDROSIS WHICH HAS BEEN SUCCESSFULLY TREATED WITH PULSE STEROID THERAPY: DOES THE HISTOPATHOLOGY PREDICT THE TREATMENT RESPONSE?
    (Literatura Medica, 2020) Oktem, Ece Ozdemir; Cankaya, Seyda; Uykur, Abdullah Burak; Erdem, Nazan Simsek; Yulug, Burak
    Acquired idiopathic generalised anhidrosis is an uncommon sweating disorder characterized by loss of sweating in the absence of any neurologic, metabolic or sweat gland abnormalities. Although some possible immunological and structural mechanisms have been proposed for this rare entity, the definitive pathophysiology is still unclear. Despite some successfully treated cases with systemic corticosteroid application, the dose and route of steroid application are controversial. Here, we present a 41-year-old man with lack of generalised sweating who has been successfully treated with high dose pulse intravenous prednisolone. We have discussed his clinical and histopathological findings as well as the treatment options in view of the current literature.