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    An Investigation of the Relationship Between the Chronotypes of Mothers Who Had Normal Delivery and Various Characteristics of Them and Their Babies
    (2022) Baytaş, Eda; Erdem, Dilek; Yılmaz, Hacı Bayram
    Introduction: Biological changes in human metabolism due to daylight and heat are expressed as circadian rhythm, and its classification according to individuals and their genetic differences is called chronotype. In recent years, there has been an increase in studies examining the relationship between circadian rhythm and birth. Purpose: This study’s first aim was to investigate the relationship between the chronotypes of mothers and time of birth, season, meridians in which they were born, and the gender of their babies. Its second aim was to examine the relationship between the birth times and chronotypes of pregnant women and the time of their deliveries. Method: The study was conducted among women presented to Alanya Training and Research Hospital Gynecology and Obstetrics Polyclinic between 01.02.2022 and 31.03.2022. The study included 147 women remembering the date and time of delivery. Participants were selected among the mothers who gave a normal birth, did not have labor induction, whose birth started with spontaneous contractions, and had a healthy pregnancy. A questionnaire form including sociodemographic characteristics, obstetric information, and Horne and Östberg's Morningness- Eveningness scale were applied face to face. One-way ANOVA, Chi-Square, and logistic regression analyses were employed to analyze the data. Results: The chronotypes of the participants revealed that 45 women (30.6%) were morning type, 90 women were intermediate type (61.2%), and 12 women were evening type (8.2%). No difference was found between the chronotype scores of the mothers and the birth hours of their babies (p = .324). There was no difference between mothers' chronotype scores and birth meridians (p = .842). In addition, no significant relationship was found between the mothers' own birth hours and the birth hours of their babies (p= .050). Conclusion: There was no relationship between birth time, season, gender, birth meridian, and chronotype. The limitation of the study may be related to the recall bias, the effect of confounding factors, and the sample size. However, we think it is an interesting field in terms of providing a different perspective on the differences in performance and mood of people with further studies regarding chronotype.
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    Changing trends in cesarean section deliveries in a tertiary hospital using the Robson Ten Group Classification
    (Rabia YILMAZ, 2023) Buhur, Ali; Erdem, Dilek
    Objective: This study aimed to identify and highlight the changing trends in cesarean deliveries in a tertiary hospital using the Robson Ten Group Classification Method: A retrospective cohort study included 103745 patients admitted to Istanbul Kanuni Training and Research Hospital's Obstetrics and Gynecology Department between January 1, 2012, and December 31, 2021. Ten groups were established based on five basic obstetric factors: parity, labor initiation, gestational age, number of fetuses, and fetal presentation. All live or dead births over 500 g or 20 gestational weeks were included in the study. Women with missing file information were excluded from the study. Total number of cesarean sections in the group, total number of women in each group, group size (%), group cesarean rate (%), absolute group contribution to general cesarean section rate (%) group contribution relative to general cesarean section rate (%) were calculated. Cesarean section indications were evaluated in 10 categories and their numbers and rates were recorded. Statistical analyzes were performed using SPSS version 24.0 for Windows. Results: Our study’s average CS rate from 2012 to 2021 was 45.77%. The largest contributions to the total cesarean section rate were in group 5 (20.69%), group 3 (5.99%), and group 1 (5.75%). Conclusion: In our study, Robson groups 5, 3, and 1 comprised the majority of contributors to the total cesarean section performed. Any effort to reduce the rate of CS should focus on these subgroups.
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    Comparison of the effectiveness and complications of transobturator tape and transvaginal tape methods in the treatment of stress urinary incontinence
    (2023) Buhur, Ali; Ünal, Ömer; Erdem, Dilek
    Aim: Comparison of the effectiveness and complications of transobturator tape and transvaginal tape methods in the treatment of stress urinary incontinence. Method: Clinical records of 106 patients who underwent surgery in Istanbul Kanuni Sultan Suleyman Training and Research Hospital due to stress urinary incontinence between January 2015 and December 2016 were retrospectively analyzed. The patients were divided into two groups. Trans obturator tape (TOT) was classified as Group 1, and transvaginal tape (TVT) was classified as Group 2. The urogenital distress inventory-6 (UDI-6) and the incontinence impact questionnaire-7 (IIQ-7) were used to determine the severity of preoperative and postoperative incontinence and objectively compare the quality of life in all patients. The ethics committee approval was obtained from the ethics committee of Kanuni Training and Research Hospital. Statistical analysis of data was performed using SPSS version 24 (SPSS Inc, Chicago, Illinois). Results: There was a significant difference between the two groups in terms of mean age, menopausal status, complications, and duration of surgery (p<0.05). In both groups, there was a significant improvement in postoperative UDI-6 and IIQ-7 tests evaluating the negative effects of urinary incontinence on daily life (p=0.01* and p=0.028*, respectively). Conclusion: A significant improvement was observed in UDI-6 and IIQ-7 scores after TOT and TVT operations. There is no significant difference between TOT and TVT methods in terms of efficacy and success in the treatment of stress urinary incontinence.
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    Endometrium karsinomu tedavisi sonrası edinilmiş vulvar Lenfanjioma sirkumskriptum : Olgu Sunumu
    (Alanya Alaaddin Keykubat Üniversitesi, 2018) Erdem, Dilek; Günizi, Özlem Ceren; Çelik, Yiğit Nilüfer
    Lenfanjiomalar, cilt ve ciltaltı dokuyu etkileyen lenfatik sistemin nadir görülen hamartomatöz malformasyonlarıdır. En sık görülen tip Lenfanjiyoma sirkumskriptumdur. Vulvar lenfanjiyoma circumscriptum (LC), yaygın görülen semptomları cinsel işlev bozukluğu ve enfeksiyon ile ağrılı, siğil bir lezyon olarak ortaya çıkabilen nadir bir durumdur. Konjenital formu çocuklarda görülürken, edinilmiş formu enfeksiyon, kanser,Crohn hastalığı, geçirilmiş pelvik cerrahiye bağlı olarak erişkinlerde oluşabilir. Bu yazıda, endometrium kanseri nedeniyle cerrahi tedavi sonrası bir yıldır vulvar lezyon ve kaşıntı şikayeti olan 73 yaşında kadın hastada edinilmiş tipte LS olgusunu sunduk. LS’yi genital siğil gibi diğer durumlardan ayırt etmek, hastalığın gidişatını değerlendirmek ve altta yatan hastalığın teşhis ve tedavisini uygulamak açısından önemlidir. Bu nedenle, bu nadir benign durumun klinik görünümünün yanında farklı histolojik görünümünü de tanımak önemlidir.
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    Evaluation of 436 cases of vaginal hysterectomy for benign indications: Experience from a tertiary hospital
    (2023) Buhur, Ali; Erdem, Dilek
    Aim: Though vaginal hysterectomy could be a minimally invasive type of hysterectomy, its preference has recently attenuated. We tend to aim to gauge the results of vaginal hysterectomies performed in our clinic for benign indications. Materials and Methods: This retrospective study was conducted on 436 Women who underwent vaginal hysterectomy for benign indications at Kanuni Sultan Suleyman Train- ing and Research Hospital. Between January 01, 2017, and December 31, 2020. Female patients aged between 40 and 85 who underwent vaginal hysterectomy for benign indica- tions was enclosed within the study. The patients with malignancy; or missing records were excluded from the study. Common indications for hysterectomy consisted of pelvic organ prolapse 385 (88.30%) and stress urinary incontinence 22(5.50%). SPSS version 24.0 was used to conduct all data analysis. Results: The four hundred thirty-six patients had a mean age of 61.07±10.0 years. The mean parity was 4.40±2.60, and the mean BMI was 31.37±1.74 kg/m2. Eighty-percent of the patients were menopausal, and 19% were of reproductive age. In our study, pelvic organ prolapse (67.88%) and abnormal uterine bleeding (18.73%) were the most common causes of hysterectomy. The major and minor complication rates were 8.02%, and 9.40%, respectively, with an overall rate of 17.42%. Conclusion: Though vaginal hysterectomy could be a minimally invasive sort of hys- terectomy; surgeons should remember complications throughout the surgery; recognizing and managing complications is crucial in VAH because it can be fatal.
  • Küçük Resim
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    Parao[onase 1 Activities in First Trimester Miscarriages
    (2021) Savaş, Hasan Basri; Erdem, Dilek
    Aim: Miscarriages are becoming increasingly important problem nowadays. First trimester pregnancy loss frequency in women of reproductive age is increasing. In this study, it is aimed to show the possible relationship between first trimester pregnancy losses and PON1 and ARY activities. Material and Method: 25 pregnant healthy women (Group 1) and 25 women with first trimester miscarriage (Group 2) in 6-14 gestational weeks were included in this study. Paraoxonase 1 and arylesterase activities of the sera samples were investigated using fully automated colorimetric methods. ANOVA test was used to compare the groups. Results: PON1 and ARY activities are statistically significantly lower in pregnant women with first trimester miscarriage compared to healthy pregnant women in first trimester analyzed by Anova test (p<0.05). Conclusion: The results of this study showed that paraoxonase 1 and arylesterase antioxidant enzyme activities can be evaluated as significant predictive clinical laboratory parameters in first trimester pregnancy losses. If this study is confirmed with larger patient groups, our research results will gain more value.
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    The effects of maternal body weight on iodine concentration in breast milk and cord blood and infant growth
    (Cambridge Univ Press, 2025) Kahraman, Ceren Sarahman; Savas, Hasan Basri; Erdem, Dilek; Ayhan, Nurcan Yabanci
    Breast milk (BM) is the only source of iodine and bioactive compounds that influence growth and development in infants. The content of BM may be influenced by maternal body mass index (BMI). The aim of this study was to investigate the effect of maternal weight on BM and cord blood iodine concentrations, growth-related hormones, infant anthropometric measurements. A total of 84 mother-infant pairs participated. Levels of leptin, adiponectin and insulin-like growth factor-I (IGF-I) in postnatal BM and cord blood were analysed by enzyme-linked immunosorbent assay (ELISA), iodine by Sandell-Kolthoff reaction. Dietary iodine intake of women was determined by food frequency questionnaire, and anthropometric measurements of infants at birth and 3 months were evaluated. Dietary iodine intake was found to be similar in normal weight (NW) and overweight/obese (OW/OB) women (p > 0.05). Breast milk iodine concentration (BMIC) was 17.4 mu g in NW, 18.2 mu g in OB/OW women. Adiponectin in cord blood and IGF-I in BM were higher OB/OW than NW women (p < 0.05). Positive correlations were found between the infant birth weight and adiponectin in BM, between the infant body weight at 3 months and leptin and adiponectin in BM, between the infant birth head circumference and IGF-I in BM (p < 0.05). In multiple linear regression model, leptin and adiponectin in BM had a positive effect on infant body weight (p < 0.05). Maternal BMI may influence infant body weight via leptin and adiponectin in BM and infant head circumference via IGF-I. No relationship was found between maternal BMI and iodine levels and anthropometric measurements of the infant. Longitudinal studies are recommended to understand the effect of BMIC on growth.
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    The relationship between the preferences of the oral glucose screening test and the levels of health literacy and perinatal anxiety of pregnancy
    (2023) Erdem, Dilek; Yardimci, Figen; Yılmaz, Hacı Bayram; Buhur, Ali
    Aim: This research aimed to determine the relationship between pregnant women's oral glucose screening test preferences and their health literacy and perinatal anxiety levels.Material and Method: The study is descriptive and cross-sectional. The sample of the study consisted of 120 pregnant women who applied to a university hospital between June and July 2022, were accepted to participate in the study, had no Turkish speaking problems, no pregestational diabetes diagnosis, no vision and hearing problems, no mental health problems, and were literate. The data were collected using face-to-face interviews with pregnant women including a questionnaire asking about the introductory characteristics of pregnant women, Turkish Health Literacy Scale-32 (TSOY-32), and Perinatal Anxiety Screening Scale (PASS). The obtained data were analyzed using one-way analysis of variance, correlation analysis, and chi-square tests.Results: 52.5% of pregnant women believed that they do not need to have an OGT. While the effect of health personnel in this decisions is 66.1%, the effect of the closed environment is 22.9%. A statistically significant negative correlation at p<.05 level was found between the Turkish health literacy scale and the Perinatal anxiety screening scale scores. Participants' believes on the necessity of OGTT test has no effect on their TSOY-32 scores or PASS scores. There is no association between the preference of women and the sub-dimensions of TSOY-32 and the PASS.Conclusion: The health literacy and perinatal anxiety levels of the pregnant women in the sample group did not affect their OGTT preferences. They stated that healthcare professionals were primarily influential in their decisions on OGTT preferences.