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Öğe An Investigation of the Relationship Between the Chronotypes of Mothers Who Had Normal Delivery and Various Characteristics of Them and Their Babies(2022) Baytaş, Eda; Erdem, Dilek; Yılmaz, Hacı BayramIntroduction: Biological changes in human metabolism due to daylight and heat are expressed as circadian rhythm, and its classification according to individuals and their genetic differences is called chronotype. In recent years, there has been an increase in studies examining the relationship between circadian rhythm and birth. Purpose: This study’s first aim was to investigate the relationship between the chronotypes of mothers and time of birth, season, meridians in which they were born, and the gender of their babies. Its second aim was to examine the relationship between the birth times and chronotypes of pregnant women and the time of their deliveries. Method: The study was conducted among women presented to Alanya Training and Research Hospital Gynecology and Obstetrics Polyclinic between 01.02.2022 and 31.03.2022. The study included 147 women remembering the date and time of delivery. Participants were selected among the mothers who gave a normal birth, did not have labor induction, whose birth started with spontaneous contractions, and had a healthy pregnancy. A questionnaire form including sociodemographic characteristics, obstetric information, and Horne and Östberg's Morningness- Eveningness scale were applied face to face. One-way ANOVA, Chi-Square, and logistic regression analyses were employed to analyze the data. Results: The chronotypes of the participants revealed that 45 women (30.6%) were morning type, 90 women were intermediate type (61.2%), and 12 women were evening type (8.2%). No difference was found between the chronotype scores of the mothers and the birth hours of their babies (p = .324). There was no difference between mothers' chronotype scores and birth meridians (p = .842). In addition, no significant relationship was found between the mothers' own birth hours and the birth hours of their babies (p= .050). Conclusion: There was no relationship between birth time, season, gender, birth meridian, and chronotype. The limitation of the study may be related to the recall bias, the effect of confounding factors, and the sample size. However, we think it is an interesting field in terms of providing a different perspective on the differences in performance and mood of people with further studies regarding chronotype.Öğe Endometrium karsinomu tedavisi sonrası edinilmiş vulvar Lenfanjioma sirkumskriptum : Olgu Sunumu(Alanya Alaaddin Keykubat Üniversitesi, 2018) Erdem, Dilek; Günizi, Özlem Ceren; Çelik, Yiğit NilüferLenfanjiomalar, cilt ve ciltaltı dokuyu etkileyen lenfatik sistemin nadir görülen hamartomatöz malformasyonlarıdır. En sık görülen tip Lenfanjiyoma sirkumskriptumdur. Vulvar lenfanjiyoma circumscriptum (LC), yaygın görülen semptomları cinsel işlev bozukluğu ve enfeksiyon ile ağrılı, siğil bir lezyon olarak ortaya çıkabilen nadir bir durumdur. Konjenital formu çocuklarda görülürken, edinilmiş formu enfeksiyon, kanser,Crohn hastalığı, geçirilmiş pelvik cerrahiye bağlı olarak erişkinlerde oluşabilir. Bu yazıda, endometrium kanseri nedeniyle cerrahi tedavi sonrası bir yıldır vulvar lezyon ve kaşıntı şikayeti olan 73 yaşında kadın hastada edinilmiş tipte LS olgusunu sunduk. LS’yi genital siğil gibi diğer durumlardan ayırt etmek, hastalığın gidişatını değerlendirmek ve altta yatan hastalığın teşhis ve tedavisini uygulamak açısından önemlidir. Bu nedenle, bu nadir benign durumun klinik görünümünün yanında farklı histolojik görünümünü de tanımak önemlidir.Öğe Parao[onase 1 Activities in First Trimester Miscarriages(2021) Savaş, Hasan Basri; Erdem, DilekAim: Miscarriages are becoming increasingly important problem nowadays. First trimester pregnancy loss frequency in women of reproductive age is increasing. In this study, it is aimed to show the possible relationship between first trimester pregnancy losses and PON1 and ARY activities. Material and Method: 25 pregnant healthy women (Group 1) and 25 women with first trimester miscarriage (Group 2) in 6-14 gestational weeks were included in this study. Paraoxonase 1 and arylesterase activities of the sera samples were investigated using fully automated colorimetric methods. ANOVA test was used to compare the groups. Results: PON1 and ARY activities are statistically significantly lower in pregnant women with first trimester miscarriage compared to healthy pregnant women in first trimester analyzed by Anova test (p<0.05). Conclusion: The results of this study showed that paraoxonase 1 and arylesterase antioxidant enzyme activities can be evaluated as significant predictive clinical laboratory parameters in first trimester pregnancy losses. If this study is confirmed with larger patient groups, our research results will gain more value.