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    Histopathological Effects of 2.45 Gigahertz Electromagnetic Radiation on the Rat Kidney, and Protective Effects of Vitamin C
    (2018) Baş, Ercan; Uçar, Hasan Murat; Baş, Funda Yıldırım; Yesılot, Sükrıye; Armagan, Ilkay; Yalçın, Arzu Didem
    Objective: To investigate the effects of electromagneticradiation (EMR) on the kidneys based on histopathologicalchanges of renal damage, and to investigate the amelioratingeffects of vitamin C (ascorbic acid) against EMR-inducedrenal damage in rats.Material-Method: Eighteen female Sprague-Dawley ratswere divided into three groups of six rats each. First groupwas the control group; these rats were kept in their cageswithout stress or electromagnetic radiation exposure. Secondgroup was exposed to 2.45 gigahertz (GHz) electromagneticradiation for 30 days. Third group was also exposed to 2.45GHz electromagnetic radiation for 30 days (1 h / day) butreceived vitamin C 250 mg / kg – 5 cc daily orally 24 hoursprior to the first exposure and daily throughout the experiment.All rats underwent nephrectomy for histopathologicalexamination.Results: There were no pathological findings in the controlgroup. Significant pathological changes were observed in EMRgroup, including tubular and glomerular damage (p<0.05).Interstitial and vascular damage was not significantly differentbetween EMR group and EMR + vitamin C group (p>0.05).Tubular and glomerular damage was less severe in EMR +vitamin C group than in EMR group (p<0.05). There was nosignificant difference between the control group and EMR +vitamin C group in terms of tubular, glomerular, interstitial, orvascular damage (p>0.05).Conclusions: Electromagnetic radiation-induced tubularand glomerular damage in the kidney was almost completelyreversed with the administration of vitamin C beforeelectromagnetic radiation exposure