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    Clinical Importance of P Wave Dispersion in Mitral Valve Prolapse
    (2024) Öncel, Can Ramazan; Köseoğlu, Cemal; Çoner, Ali
    Objective: Mitral valve prolapse (MVP) is a widespread valvulopathy present in 2–6% of the population, affecting more than 170 million people globally. The objective of this study was to assess P wave dispersion (PWD) in patients with MVP to identify the presence of cardiovascular autonomic dysfunction and the potential risk of developing atrial arrhythmias in these patients. Materials and Methods: The study included 40 healthy control participants (Group 1), 41 patients with non-classic MVP (Group 2), and 36 patients with classic MVP (Group 3). Demographic and clinical characteristics were documented upon admission. An electrocardiographic assessment was conducted to quantify PWD values for both patients and the control group. Results: The minimum P wave duration was lower in classic MVP patients than in controls and non-classic MVP patients (63±3.6 vs. 70±2.0, p<0.001; 63±3.6 vs. 63±3.6, p<0.001, respectively). P wave dispersion was higher in classic MVP patients than in non-classic MVP patients (47.3±3.2 vs. 39.0±2.3, p=0.001). A significant positive correlation was detected between PWD and maximum P wave duration (Pmax), minimum P wave duration (Pmin), maximal leaflet displacement, maximal leaflet thickness, and left atrial diameter (LAD) (r=0.723, p<0.001; r=- 0.771, p<0.001; r=0.557, p<0.001; r=0.770, p<0.001; r=0.517, p<0.001, respectively). Maximum leaflet thickness and maximum leaflet displacement were independent predictors of increased PWD in linear regression analysis (?=1.456, p<0.001, ?=-0.851, p<0.001). Conclusion: Patients with classic MVP exhibited prolonged PWD values compared with non-classic MVP patients and normal controls.
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    Correct Interpretation of Exaggerated Blood Pressure Response During Exercise Tests
    (2024) Çoner, Ali
    [Abstract Not Available]
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    Determining ECG Parameters for Electrical Risk Score in Patients with Non-ST Elevation Myocardial Infarction
    (2025) Öncel, Can Ramazan; Çoner, Ali; Köseoğlu, Cemal
    [Abstract Not Available]
  • Küçük Resim
    Öğe
    Factors Associated with Aortic Stiffness Index, Aortic Velocity Propagation, and Epicardial Fat Thickness in Pregnancy
    (Kare Publications, 2025) Köseoğlu, Cemal; Öncel, Can Ramazan; Çoner, Ali
    I found the study titled “The Effect of Number of Pregnancies on Aortic Stiffness Index, Aortic Velocity Propagation, and Epicardial Fat Thickness” by Şaylık et al.,1 published in the Archives of the Turkish Society of Cardiology, to be highly interesting. We would like to highlight several important aspects of this well-written study.
  • Küçük Resim
    Öğe
    In-Hospital Cardiac Complications in Legionnaires’ disease: A Single Center Experience of 32 Patients
    (2021) Akıncı, Sinan; Çoner, Ali; Erdoğan, Haluk
    Introduction: Legionella species frequently causes Legionnaires’ disease (LD), a community-acquired pneumonia (CAP). Although data on cardiac events during the course of CAP can be found in the literature, there has been little research on the same issue in LD patients specifically. This study aimed to investigate cardiac complications in the course of LD. Materials and Methods: A total of 32 patients hospitalized with CAP and who received a definitive diagnosis of Legionella infection were identified from the hospital database and included in the study population. The patients’ electronic and written records were evaluated for possible cardiac complications. Results: Mean age was 65±13.5 years and 50% of the subjects were males. Seven patients died during hospitalization. Cardiovascular events were detected in 11 patients. New-onset atrial fibrillation was the most frequent event and was detected in 8 patients (25%), while two patients experienced a myocardial infarction, and one patient was diagnosed with myocarditis. The cardiovascular events were significantly related to the pneumonia severity index (PSI) score and need for intensive care unit. Conclusion: Although LD rarely involves the heart, it can often cause cardiac complications, and the frequency increases in parallel with the severity of the disease. This study indicates that patients with LD should be carefully followed for possible cardiac complications.
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    Koroner arter Bypass greft cerrahisi hastalarının nativ koroner Arterlerinde yeni kronik total Oklüzyon gelişimi
    (Alanya Alaaddin Keykubat Üniversitesi, 2020) Çoner, Ali; Akıncı, Sinan; Akbay, Ertan; Budak, Ali Baran; Saba, Tonguç; Müderrisoğlu, Haldun
    Amaç: Koroner arter bypass greftleme (KABG) cerrahisi hastalarının postoperatif klinik takibinde preoperatif olarak tam tıkalı olmayan nativ koroner arterlerin kronik total oklüde (KTO) hale gelmesi sık görülse de, seyriyle ilgili veriler kısıtlıdır. Çalışmamızın amacı postoperatif dönemde nativ koroner arterlerde yeni KTO gelişim sıklığını ve bu konuda rol oynayan faktörleri araştırmaktır. Yöntem: Başkent Üniversitesi Hastanesi Alanya Uygulama ve Araştırma Merkezi’nde gerçekleştirilen tüm KABG operasyonları bilgisayar sisteminden tarandı ve postoperatif ilk 6 aylık dönemden sonra rekürren koroner anjiyografi (KAG) prosedürü uygulanan hastalar çalışma grubuna alındı. Rekürren KAG görüntüleri yeni KTO gelişimi açısından değerlendirildi ve nativ koroner arterlerde yeni KTO gelişimine yol açan demografik ve anjiyografik özellikler lojistik regresyon analizi kullanılarak test edildi.Bulgular: Rekürren KAG yapılmış olan 73 KABG hastası istatistiksel analize dahil edildi (Ortalama yaş 65.2 ± 9.8 yıl; erkek cinsiyet %76.7). Preoperatif olarak tam tıkalı olmayan ve greftlenmiş olan 218 nativ koroner arter incelendi ve 119’unda (%54.5) yeni KTO saptandı. Preoperatif proksimal darlığın ?%90 olması 3 kat daha fazla yeni KTO gelişimi ile ilişkili bulundu (%67.8 vs. %22.2) (p&lt;0.001). İkili antiplatelet tedavisinin nativ koroner arterlerin açıklığını koruyucu rolü olduğu tespit edildi (HR:-0.259; %95 CI:-0.475’den -0.017’ye; p=0.036). Sonuç: Nativ koroner arterlerde postoperatif yeni KTO gelişimi CABG hastalarında sık görülmektedir. Preoperatif darlığın daha ciddi olması ve ikili antiplatelet tedavinin yokluğu yeni KTO gelişimi için temel faktörler olarak bulundu.
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    Lipid lowering and additional pleiotropic effects of statins
    (2025) Çoner, Ali; Aslan, Ahmet
    Statins are among the most commonly prescribed drugs worldwide today. They are primarily effective in primary and secondary prevention of cardiovascular diseases with their cholesterol-lowering properties. Recent studies have reported that statin derivatives have positive outcomes in different clinical conditions with different mechanisms, in addition to their lipid-lowering effects. In this paper, we aimed to discuss the pleiotropic effects of statins in addition to their protective effects in cardiovascular practice.
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    Management of new diagnosed rectum cancer in the course of acute myocardial infarction
    (Alanya Alaaddin Keykubat Üniversitesi, 2018) Çoner, Ali; Çiçek, Davran; Akıncı, Sinan; Balcıoğlu, Serhat; Aydınalp, Alp; Müderrisoğlu, Haldun
    Expected life-spans increase all over the world and in our clinical experience we see atherosclerotic vascular diseases and malignant neoplasms more commonly. Herein, we want to present a case with coexistence of acute myocardial infarction and new diagnosed rectum cancer. Close monitoring is essential in these patients however stent thrombosis can be seen and patient and relatives should be informed about the risks and possible treatment choices in a detailed way.
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    Management of the heparin induced thrombocytopenia in the course of acute myocardial infarction
    (Alanya Alaaddin Keykubat Üniversitesi, 2020) Çoner, Ali; Akıncı, Sinan; Akbay, Ertan
    Heparin-induced thrombocytopenia (HIT) is a difficult clinical presentation to deal with and we know little about the management of these patients. Stopping of heparin is essential in treatment but some patients may need anticoagulation in the follow-up; however, we do not have enough data about the patients with a need of anticoagulant usage. We want to present a myocardial infarction patient who developed type I HIT after exposure to unfractionated heparin with a need of anticoagulation at the same time.
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    Pericardial bleeding following covered stent thrombosis: sharp blade on both sides
    (Alanya Alaaddin Keykubat Üniversitesi, 2018) Çoner, Ali; Çiçek, Davran; Akıncı, Sinan; Saba, Tonguç; Müderrisoğlu, Haldun
    Advancements in coronary stent technology encourage interventional cardiologists in performing more complex, percutaneous interventions. Coronary perforation is a lethal complication of percutaneous coronary artery interventions and should be managed within seconds to minutes. Despite technological advancements, coronary perforation incidence has not declined over the years. This consistent incidence of coronary perforation may be related to increased number of complex, percutaneous coronary artery interventions. Covered stent implantation is a life-saving solution during the course of this emergent complication but also carries its own short and long term risks in the follow-up of these patients. Herein this report, we aimed to present a successful management of a case of coronary perforation by covered stent implantation but complicated during in-hospital period in the following days.
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    Predicting Postoperative Atrial Fibrillation Using HARMS2-AF Score
    (2024) Öncel, Can Ramazan; Köseoğlu, Cemal; Dagasan, Goksel; Çoner, Ali; Ayhan, Selçuk; Akkaya, Özgür; Karahan, Oğuz
    Background: Postoperative atrial fibrillation (POAF) remains a common complication after cardiac surgery. The ability to accurately identify patients at risk through previous risk scores is limited. This study aimed to evaluate the new HARMS2-AF risk score to pre- dict POAF after coronary artery bypass grafting (CABG) surgery. Methods: In this retrospective cohort study, we included 265 patients undergoing CABG surgery from 2022-2023. Data were obtained from the medical files of the patients and hospital records. Each patient was assigned a HARMS2-AF risk score. A univariate and multivariate regression analyses were done to analyze independent predictors of POAF. Results: Of 265 patients, 49 had postoperative atrial fibrillation. HARMS2-AF score was significantly higher in patients with POAF. Age, sleep apnea, left atrial diameter (LAd), and HARMS2-AF score were independently associated with POAF. A HARMS2-AF score ? 4.5 predicted POAF with 91% sensitivity and 64% specificity (AUC = 0.787, 95% CI = 0.731- 0.842, P < .001). Conclusion: The HARMS2-AF score is a strong predictor of atrial fibrillation (AF) develop- ment after isolated CABG surgery. It can be used as a novel stratification tool to estimate AF after cardiac surgery.