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    Diş Materyallerde Kadmiyum Toksisitesi: Ağız Kanserinde Rol Oynayabilir mi? Sistematik Bir Derleme
    (Akdeniz Üniversitesi, 2022) Şatır, Samed; Çimen, Tansu; Köse, Mehmet Numan; Bozoğulları, Hatice Nalan; Çankaya, Tülin Doğan; Er, Kürşat
    Kanserojen/toksik eser elementlerden biri olan kadmiyum, tütüne bağlı oral kanser (OK) araştırmalarında önemli bir alt başlıktır. Kadmiyumun dental materyallerdeki toksisitesi ve OK oluşumundaki rolü PubMed'deki makaleler kullanılarak araştırıldı. Böylece, bu veri tabanından toplam 13 çalışma incelemeye dahil edilmiştir. Dental materyallerdeki kadmiyumun genel olarak toksik etkilere neden olmayacak düzeyde olduğu ortaya konmuştur. Ayrıca tütün ürünleri, gıdalar, hava kirliliği ve içme suyu gibi kadmiyumun önemli kaynaklarının bulunduğu günümüzde kadmiyum kaynaklı OK oluşumunda dental materyallerin etyolojik faktörler arasında olamayacağı söylenebilir.
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    Öğe
    Efficacy of different irrigation activation systems on bacterial extrusion
    (2022) Uğur, Aydın Zeliha; Erdönmez, Demet; Ateş, Melis Oya; Çankaya, Tülin Doğan
    Dear Editor,In our study, standard needle irrigation was used as a control group. In addition, similar to the usage in the title of our article, EndoVac is mentioned as an irrigation acti-vation method in the articles below:
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    Öğe
    Endodontik İrrigasyon Solüsyonlarının One Curve Eğesinin Döngüsel Yorgunluk Direncine Olan Etkisinin Karşılaştırılması: İn Vitro Bir Çalışma
    (2023) Çankaya, Tülin Doğan; Özkan, Hatice Büyüközer; Sürme, Koray
    Amaç: Sodyum hipoklorit (NaOCl), klorin dioksit (ClO2), etilen diamin tetra asetik asit (EDTA) ve etidronik asit (HEDP) solüsyonlarının One Curve (OC) eğesinin döngüsel yorulma direncine etkisini değerlendirmektedir. Gereç ve Yöntemler: 60 adet OC eğesi %5 NaOCl, %3,5 ClO2, %17 EDTA, %18 HEDP solüsyonu ve distile su ile muamele edilmek üzere 5 gruba (n= 12) ayrıldı. Her grupta bulunan eğeler kanal içi sıcaklığa (35±1 °C) getirilmiş ilgili solüsyonlara daldırılarak 5 dk bekletildi. Ardından eğeler 60° kurvatür açısına, 5 mm yarıçapına ve 1,5 mm çapına sahip 17 mm uzunluğunda paslanmaz çelik blokta test edildi. Eğeler X-Smart Plus endomotor ile kırılıncaya kadar kullanıldı. Eğelerin kırılana kadar olan tur sayıları ve süreleri ve kırık parça uzunlukları kaydedildi. P<0,05 anlamlılık derecesinde verilerin istatistiksel analizi için tek yönlü varyans analizi ve Tukey testi kullanıldı. Bulgular: Eğelerin döngüsel yorgunluk direnci arasında istatistiksel olarak fark gözlenmedi (P>0,05). Kırık parça uzunlukları büyükten küçüğe sırasıyla; distile su, HEDP, EDTA, NaOCl, ClO2 olarak bulundu. Test edilen solüsyonlar kırık parça uzunlukları açısından anlamlı fark gösterdi (P<0,05). Sonuç: Test edilen tüm solüsyonlar OC eğesinin döngüsel yorgunluk direnci üzerinde benzer etki sergilemiştir. Bununla birlikte kırık parça uzunluğu en uzun distile su grubunda iken, en kısa ClO2 grubunda bulunmuştur.
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    Öğe
    Evaluation of Residual Root Canal Sealer Removal Efficacy of Different Irrigation Activation Techniques by Confocal Laser Microscopy Analysis
    (2023) Aydın, Zeliha Uğur; Altunbaş, Demet; Koşumcu, Sevim; Meşeci, Büşra; Çankaya, Tülin Doğan
    Objective: The purpose of this study was to use confocal laser microscopy analysis to evaluate the effectiveness of conventional needle irrigation (CNI), EndoActivator (EA), and EDDY during endodontic retreatment. Methods: This study included 45 maxillary incisor teeth with a single root and canal. Root canals were prepared with ProTaper Universal files (Dentsply Sirona, Ballaigues, Switzerland) and obturated with labeled sealer mixed with 0.1% Rhodamine B and gutta percha according to single cone techniques. Initial root canal filling material was removed using ProTaper Universal Retreatment files and F4 files. Teeth randomly were divided into 3 groups (n = 15) depending on the activation technique: CNI, EA (Dentsply, Tulsa Dental Specialties, Tulsa, OK), and EDDY (VDW, Munich, Germany). Confocal laser microscopy was used to evaluate the penetration area, depth, and percentage of the residual sealer in the apical, middle, and coronal sections after irrigation activation. Results: In all sections, the EDDY group had a lower penetration area of residual sealer than the CNI group (P< .05). In comparison to the coronal section, the penetration percentage of the CNI and EA groups was lower in the apical section (P< .05). In the CNI group, the penetration depth was higher at the coronal section than at the apical and middle sections (P< .05), and it was higher at the coronal section than at the apical section. Conclusion: Within the limitations of this study, none of the activation systems tested could completely remove the residual sealer. However, the lowest residual sealer was seen after using EA and EDDY.
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    Öğe
    Investigation of pH Values of Ready to Use Dental EDTA Solutions of Different Brands: In Vitro Study
    (Akdeniz Üniversitesi, 2025) Kuloğlu, Bircan; Özkan, Hatice Büyüközer; Çankaya, Tülin Doğan
    Aim The removal of the smear layer is a critical step in the success of root canal treatment. It is known that the effectiveness of EDTA solutions can vary, particularly depending on their pH levels. The aim of this study was to compare the room temperature pH values and cost per liter of eight different brands of 17% EDTA solutions available on the Turkish market. Material and Methods In this study, eight different commercially available 17% EDTA solutions were procured from the market. The pH values of the solutions were measured at room temperature using a pH meter, with three separate measurements taken for each solution, and the average values were calculated. Additionally, the cost per liter of each product was determined. The collected data were analyzed comparatively. Results The pH values of Woolin Endo, Promida, Cool & EDTA, and Werax brands were measured as 13.00 ± 0.4. The pH values of Imicryl and Saver brands were found to be 10.00 ± 0.8, while those of AQUA Solution and Cerkamed Endo-Solution brands were measured as 7.4 ± 0.1. In terms of price analysis, Cool & EDTA had the lowest cost per liter. AQUA Solution was identified as the most economical product among those with a neutral pH value. Conclusion It is important for companies in the market to declare the pH value as it affects the physical properties of the solution.
  • Küçük Resim
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    The effect of various canal contents on the accuracy of two electronic apex locators in detecting different size of root perforations
    (2021) Çankaya, Tülin Doğan; Aydın, Zeliha Uğur; Altunbaş, Demet
    Objective: This study was to investigate the effect of different canal contents on the accuracy of Gold Reciproc Motor (GRM; VDW, Munich, Germany) and DentaPort ZX (Morita Co, Kyoto, Japan) in the determination of artificial root perforations. Methods: Forty mandibular premolar teeth were included in this study. The crowns of the teeth were removed and the root lengths were standardized to be 14 +/- 1 mm. Roots were divided into 2 groups (n=20). Artificial root perforations were created 0.5 +/- 0.1mm and 1 +/- 0.1 mm in size respectively. The actual lengths (AL) up to the perforation areas were measured under the stereomicroscope. Electronic measurements (EL) were obtained by GRM and DentaPort ZX in dry conditions and the presence of NaOCl (5.25%), EDTA (17%) and blood. The difference was calculated by subtracting the ALs from the ELs. This difference was positive when the measurement was longer than the AL and negative when the measurement was shorter. The Friedman and Wilcoxon signed-rank tests were used to analyze the data (p<0.05). Results: There were no significant differences amongst the different intracanal conditions for both apex locators in teeth with perforation of 1 mm. In the teeth with a perforation of 0.5 mm DentaPort ZX measurements were not affected by intracanal conditions and the most accurate measurement was obtained when the canal was dry with GRM. Conclusion: Within the limitation of this study, intracanal conditions did not affect the measurements of DentaPort ZX in both perforation sizes, whereas in 0.5 mm perforation size, GRM measurements were affected by intracanal conditions..