Cakir, Ozlem Ozer2026-01-242026-01-2420192587-0319https://search.trdizin.gov.tr/tr/yayin/detay/376675https://doi.org/10.30565/medalanya.551550https://hdl.handle.net/20.500.12868/3773Aim: We aimed to show the relationship between blood neutrophil to lymphocyteratio that is systemic inflammatory marker and tumor s ize, tumor number, macrovascular invasion at the time of diagnosis in patients with hepatocellular carcinoma.Methods: A total 48 patients diagnosed with hepatocellular carcinoma were includedin our study. The patients were divided into two groups according to themedian neutrophil to lymphocyte ratio.Results: A total of 48 patients (11 female, 37 male) were included in our study.The mean age of the patients were 67.18±9.51 years-old. The median neutrophil tolym-phocyte ratio was 3.17. There were significant association between neutrophil tolym-phocyte ratio > 3.17 and macrovascular invasion, the tumor number> 3, thetumor size> 5 cm, Child-Turcot-Pugh score, Model for End-stage Liver DiseaseSodium score, C-reactive protein and blood sodium level (p: 0.005, p: 0.009, p<0.001, p: 0.003, p:0.008, p: 0.035 and p < 0.001, respectively). Multiple logisticlineer regres-sion analysis showed that NLR> 3.17 was an independent predictor oftumor size> 5 cm and hyponatremia in patients with hepatocellular carcinoma (p:0.010, p: 0.012, respectively).Conclusions: The value of blood neutrophil to lymphocyte ratio at the time of diagnosis in patients with hepatocellular carcinoma was a good predictor of tumor sizeand grade of disease.eninfo:eu-repo/semantics/openAccessGenel ve Dahili Tıp,OnkolojiArticle10.30565/medalanya.55155033207212376675