Dulgerbaki, Cigdem2026-01-242026-01-2420251574-14431574-1451https://doi.org/10.1007/s10904-025-03772-xhttps://hdl.handle.net/20.500.12868/5546Conventional nanomaterials are used in electrochemical glucose non-enzymatic sensing, but their widespread application is restricted by high costs and complex preparation procedures. This study explores the use of nickel hydroxide (Ni(OH)2), which was deposited onto the entire surface of a screen-printed gold electrode (SPGE) through one-step electrodeposition process, serving as an interface material for non-enzymatic glucose sensing. The surface morphology, composition and electrochemical properties of SPGE/Ni(OH)2 were investigated using scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), elemental mapping, cyclic voltammetry (CV) and chronoamperometry (CA). CV and CA results revealed that SPGE/Ni(OH)2 exhibited excellent electrocatalytic activity towards glucose. The oxidation current was directly proportional to glucose concentrations ranging from 10 mu M to 200 mu M. Furthermore, the glucose sensor demonstrated a low detection limit of 1.8 mu M in a basic solution and exhibited excellent selectivity. With its facile preparation and reliable performance, this sensor is a promising candidate for the next generation non-enzymatic glucose diagnostic devices.eninfo:eu-repo/semantics/openAccessNickel hydroxideNon-enzymatic sensorGlucose detectionElectrodepositionScreen printed gold electrodeArticle10.1007/s10904-025-03772-x358711071282-s2.0-105003462101Q1WOS:001475721300001Q1