Avcı, MustafaKozaci, Nalan2026-01-242026-01-2420252822-4078https://search.trdizin.gov.tr/tr/yayin/detay/1316289https://doi.org/10.4274/globecc.galenos.2024-65365https://hdl.handle.net/20.500.12868/4035Objective: This study aimed to investigate the role of oxidant and antioxidant levels in the diagnosis of acute pulmonary embolism (APE). Materials and Methods: Participants diagnosed with APE were included in group 1, and healthy volunteers were included in Group 2. In addition, Group 1 was divided into two groups according to 30-day mortality. Results: Sixty-five participants diagnosed with APE were included in Group 1. A total of 52 healthy volunteers were included in Group 2. The total antioxidant capacity (TAC) levels of Group 1 were lower than those of Group 2, and the total oxidant capacity (TOC), oxidative stress index (OSI), and ischemia-modified albumin levels were higher. When receiver operating characteristic analysis was performed for TAC, TOC, OSI, and ischemia-modified albumin, the highest area under the curve was found for OSI, TOC, and ischemia-modified albumin, respectively. Fifteen (23%) participants in Group 1 died within 30 days of admission to the emergency department (Group 1A), and 50 (77%) survived after 30 days (Group 1B). Conclusion: The oxidant-antioxidant balance is impaired in APE. Therefore, oxidants and antioxidants can be used to diagnose and exclude patients with suspected APE.eninfo:eu-repo/semantics/openAccessOxidative stressAntioxidantischemiapulmonary embolismoxidantArticle10.4274/globecc.galenos.2024-653654114221316289