Isik, MerveCankaya, Tulin DoganAydin, Zeliha Ugur2026-01-242026-01-2420251462-64461867-5646https://doi.org/10.3290/j.cjdr.b6260628https://hdl.handle.net/20.500.12868/5367Objective: To compare the results of non-surgical endodontic retreatment (NSER) applied in a single visit between type 2 diabetes mellitus (DM) patients with teeth with apical periodontitis (AP) and healthy individuals. Methods: The subjects enrolled were divided into two groups. The type 2 DM group was composed of 26 single-rooted mandibular teeth belonging to 26 patients (aged 45.04 +/- 10.13 years; 19 women and 7 men) who did not have any other systemic disease. The control group, meanwhile, consisted of 27 single-rooted mandibular teeth from 27 patients (aged 37.78 +/- 12.61 years; 15 women and 12 men) with no systemic disease. Both groups received single-visit non-surgical endodontic retreatment. Periapical radiographs were taken with a parallel technique before NSER and at least 6 months after treatment. Periapical index scores (PAI) for the relevant teeth were recorded. The data obtained were analysed statistically. P <0.05 was considered significant. Results: In both groups, postoperative PAI values decreased compared to the initial values after NSER treatment applied in a sin gle visit (P <0.05); however, there was no significant difference in the change in PAI values over time between the control and type 2 DM groups (P > 0.05). There was also no significant difference in healing between men and women in both groups (P >0.05). Conclusion: Following single-visit NSER in teeth with apical periodontitis, similar treatment outcomes were achieved in patients with type 2 DM and healthy individuals.eninfo:eu-repo/semantics/closedAccessdiabetes mellitusendodontic treatmentperiapical indexArticle10.3290/j.cjdr.b626062828213914640497767WOS:001511313800006Q4