Erdogan, HalukArslan-Akdag, BetulGuldal, MustafaErdogan, Askin2026-01-242026-01-2420251301-143X1309-1484https://doi.org/10.36519/kd.2025.5083https://hdl.handle.net/20.500.12868/4815A 40-year-old female patient was admitted to the emergency department with high-grade fever, headache, generalized joint pain, and a history of tick attachment. On physical examination, body temperature was 39.5 degrees C, with diffuse maculopapular rash and conjunctival hyperemia. Laboratory findings include mild anemia, profound lymphopenia, severe thrombocytopenia, severe hyponatremia, markedly elevated procalcitonin and C-reactive protein (CRP) levels, abnormal liver function tests, and severe hypocalcemia. Indirect fluorescent antibody (IFA) testing revealed positivity for both immunoglobulin M (IgM) and immunoglobulin G (IgG) against Rickettsia conorii. The patient responded well to doxycycline therapy and was discharged in good condition. To the best of our knowledge, this is the first reported case of Mediterranean spotted fever identified in the Mediterranean region of T & uuml;rkiye.trinfo:eu-repo/semantics/openAccessMediterranean spotted feverRickettsia conoriiRhipicephalus sanguineusArticle10.36519/kd.2025.50833831931972-s2.0-105017902272Q4WOS:001640901300008Q3