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dc.contributor.authorKubat, Mehmet
dc.contributor.authorKarabulut, Zülfikar
dc.date.accessioned2021-02-19T21:20:46Z
dc.date.available2021-02-19T21:20:46Z
dc.date.issued2020
dc.identifier.issn1022-386X
dc.identifier.urihttps://doi.org/10.29271/jcpsp.2020.6.595
dc.identifier.urihttps://hdl.handle.net/20.500.12868/663
dc.descriptionPubMed: 32703343en_US
dc.description.abstractObjective: To investigate the effectiveness of tumor volume dependent mean diameter (Rmax) in determining axillary lymph node metastasis positivity instead of the largest diameter (Dmax) in breast cancer. Study Design: Descriptive study. Place and Duration of Study: Department of General Surgery, Ankara Training and Reseach Hospital, Turkey, from January 2009 to December 2018. Methodology: Patients with breast cancer, who underwent modified radical mastectomy and lumpectomy and axillary lymph node dissection due to invasive carcinoma, included in this study. Approximate vTm was calculated from the obtained tumor specimen dimensions using ellipsoid volume formula. From the sphere volume formula, Rmax, which gives the same vTm value, was reversely calculated. Efficacy and usability of Rmax value were evaluated on nomograms that are available online; and are used most frequently owing to its ease of use. Results: In 305 patients, mean Dmax was 3.4 ±1.8 cm, mean vTm was 17.9 ±35.9 cm3, and mean Rmax was 2.6 ±1.4 cm. For the distinction of ALNM positive and negative patients, Dmax significant [Area Under Curve (AUC) 0.709], Rmax significant [AUC 0.748] and vTm significant [AUC 0.748] efficacy was considered. Conclusion: When the relationships of Dmax and vTm with ALNM were compared in breast cancer cases, the efficacy of vTm is higher. It was found that vTm and Rmax can be used instead of Dmax. The relation of Rmax parameter with ALNM was found to be higher. When Rmax was used in nomogram samples, which are currently used in predicting ALNM positivity, it increased nomogram efficacy. © 2020 College of Physicians and Surgeons Pakistan. All rights reserved.en_US
dc.language.isoengen_US
dc.publisherCollege of Physicians and Surgeons Pakistanen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBreast neoplasmen_US
dc.subjectLymphatic metastasisen_US
dc.subjectTumor burdenen_US
dc.subjectTumor diameteren_US
dc.subjectTumor volumeen_US
dc.titleComparison of tumor volume dependent mean diameter with the longest diameter and tumor volume in assessing axillary lymph nodes in breast canceren_US
dc.typearticleen_US
dc.contributor.departmentALKÜen_US
dc.contributor.institutionauthor0-belirlenecek
dc.identifier.doi10.29271/jcpsp.2020.6.595
dc.identifier.volume30en_US
dc.identifier.issue6en_US
dc.identifier.startpage595en_US
dc.identifier.endpage600en_US
dc.relation.journalJournal of the College of Physicians and Surgeons Pakistanen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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