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dc.contributor.authorErtuğrul, Ceylan Çağıl
dc.contributor.authorKırzıoğlu, Zühal
dc.contributor.authorAktepe, Evrim
dc.contributor.authorSavas, Hasan Basri
dc.date.accessioned2021-02-19T21:16:25Z
dc.date.available2021-02-19T21:16:25Z
dc.date.issued2018
dc.identifier.issn1119-3077
dc.identifier.urihttps://doi.org/10.4103/njcp.njcp_385_17
dc.identifier.urihttps://hdl.handle.net/20.500.12868/423
dc.descriptionWOS: 000443749400021en_US
dc.descriptionPubMed: 30156210en_US
dc.description.abstractIntroduction: This study investigated the dental health problems and saliva characteristics of children under psychostimulant therapy for attention-deficit hyperactivity disorder (ADHD). Materials and Methods: One hundred and twenty children aged 7-12 years were divided into three groups. Groups 1-2 comprised children diagnosed with ADHD: those who had not yet started psychostimulant therapy (Group 1) and those already receiving long-term psychostimulant therapy (Group 2). Group 3 comprised healthy, nonmedicated children. Possible side effects of psychostimulants were investigated at the beginning of study in Group 2 and after 3 months drug use in Group 1. Bruxism and dental erosion prevalence, salivary Streptococcus mutans count, buffering capacity, and stimulated salivary flow rate (SSFR) were measured, and salivary a-amylase, calcium, total protein, and proline-rich acidic protein (PRAP) levels were quantified in the beginning of the study. Data were analyzed using the Kruskal-Wallis test. Results: The most frequently reported side effects of psychostimulants were decreased appetite, dry mouth, and increased fluid consumption. The prevalence of bruxism and dental erosion was higher in Groups 1 and 2 than in Group 3, but the differences were not significant (P > 0.05). In Group 2, subjective dry mouth feel was reported by 32.5% of patients and 17.5% had a very low SSFR. Salivary a-amylase, calcium, total protein, and PRAP levels were lower in Group 2 than the others, but the differences were not significant (P > 0.05). Conclusions: ADHD and psychostimulant therapy do not appear to be significantly related to decreasing SSFR or protective saliva components against dental caries. However, a systematic investigation of the long-term safety of psychostimulants is needed. The most effective method of maintaining dental health of children with ADHD is frequent appointments focusing on oral hygiene practices accompanied by dietary analyses.en_US
dc.language.isoengen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAttention-deficit hyperactivity disorderen_US
dc.subjectbruxismen_US
dc.subjectdental erosionen_US
dc.subjectdry mouthen_US
dc.subjectpsychostimulantsen_US
dc.subjectsaliva biochemical componentsen_US
dc.subjectsalivary flow rateen_US
dc.titleThe effects of psychostimulants on oral health and Saliva in children with attention deficit hyperactivity disorder: A case-control studyen_US
dc.typearticleen_US
dc.contributor.departmentALKÜen_US
dc.contributor.institutionauthor0-belirlenecek
dc.identifier.doi10.4103/njcp.njcp_385_17
dc.identifier.volume21en_US
dc.identifier.issue9en_US
dc.identifier.startpage1213en_US
dc.identifier.endpage1220en_US
dc.relation.journalNigerian Journal of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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