dc.contributor.author | Ertuğrul, Ceylan Çağıl | |
dc.contributor.author | Kırzıoğlu, Zühal | |
dc.contributor.author | Aktepe, Evrim | |
dc.contributor.author | Savas, Hasan Basri | |
dc.date.accessioned | 2021-02-19T21:16:25Z | |
dc.date.available | 2021-02-19T21:16:25Z | |
dc.date.issued | 2018 | |
dc.identifier.issn | 1119-3077 | |
dc.identifier.uri | https://doi.org/10.4103/njcp.njcp_385_17 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12868/423 | |
dc.description | WOS: 000443749400021 | en_US |
dc.description | PubMed: 30156210 | en_US |
dc.description.abstract | Introduction: This study investigated the dental health problems and saliva characteristics of children under psychostimulant therapy for attention-deficit hyperactivity disorder (ADHD). Materials and Methods: One hundred and twenty children aged 7-12 years were divided into three groups. Groups 1-2 comprised children diagnosed with ADHD: those who had not yet started psychostimulant therapy (Group 1) and those already receiving long-term psychostimulant therapy (Group 2). Group 3 comprised healthy, nonmedicated children. Possible side effects of psychostimulants were investigated at the beginning of study in Group 2 and after 3 months drug use in Group 1. Bruxism and dental erosion prevalence, salivary Streptococcus mutans count, buffering capacity, and stimulated salivary flow rate (SSFR) were measured, and salivary a-amylase, calcium, total protein, and proline-rich acidic protein (PRAP) levels were quantified in the beginning of the study. Data were analyzed using the Kruskal-Wallis test. Results: The most frequently reported side effects of psychostimulants were decreased appetite, dry mouth, and increased fluid consumption. The prevalence of bruxism and dental erosion was higher in Groups 1 and 2 than in Group 3, but the differences were not significant (P > 0.05). In Group 2, subjective dry mouth feel was reported by 32.5% of patients and 17.5% had a very low SSFR. Salivary a-amylase, calcium, total protein, and PRAP levels were lower in Group 2 than the others, but the differences were not significant (P > 0.05). Conclusions: ADHD and psychostimulant therapy do not appear to be significantly related to decreasing SSFR or protective saliva components against dental caries. However, a systematic investigation of the long-term safety of psychostimulants is needed. The most effective method of maintaining dental health of children with ADHD is frequent appointments focusing on oral hygiene practices accompanied by dietary analyses. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Wolters Kluwer Medknow Publications | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Attention-deficit hyperactivity disorder | en_US |
dc.subject | bruxism | en_US |
dc.subject | dental erosion | en_US |
dc.subject | dry mouth | en_US |
dc.subject | psychostimulants | en_US |
dc.subject | saliva biochemical components | en_US |
dc.subject | salivary flow rate | en_US |
dc.title | The effects of psychostimulants on oral health and Saliva in children with attention deficit hyperactivity disorder: A case-control study | en_US |
dc.type | article | en_US |
dc.contributor.department | ALKÜ | en_US |
dc.contributor.institutionauthor | 0-belirlenecek | |
dc.identifier.doi | 10.4103/njcp.njcp_385_17 | |
dc.identifier.volume | 21 | en_US |
dc.identifier.issue | 9 | en_US |
dc.identifier.startpage | 1213 | en_US |
dc.identifier.endpage | 1220 | en_US |
dc.relation.journal | Nigerian Journal of Clinical Practice | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |