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dc.contributor.authorAkdeniz, Aydan
dc.contributor.authorMehtap, Özgür
dc.contributor.authorKarakuş, Volkan
dc.contributor.authorÜnal, Serkan
dc.contributor.authorAygün, Kemal
dc.contributor.authorTemel, Gülhan Örekici
dc.contributor.authorTombak, Anıl
dc.contributor.authorTiftik, Eyüp Naci
dc.date.accessioned2023-06-02T06:12:14Z
dc.date.available2023-06-02T06:12:14Z
dc.date.issued2021en_US
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/506770/are-platelet-related-parameters-predictive-of-the-prognosis-of-hodgkins-lymphoma
dc.identifier.urihttps://hdl.handle.net/20.500.12868/2211
dc.description.abstractObjective: Hodgkin’s lymphoma has a good prognosis unless it has relapsed or become refractory. The predictive value of platelet (Plt)-related parameters, namely, mean Plt volume (MPV), plateletcrit (PCT), Plt distribution width, and Plt, is shown in some solid tumors and hematological malignancies, but it remains unknown in Hodgkin’s lymphoma. This study aimed to define their values and effects on staging and relapsing status in patients with Hodgkin’s lymphoma by comparing them with those in healthy subjects. Methods: Values of Plt-related parameters of 217 patients with Hodgkin’s lymphoma and 205 healthy individuals were documented and compared according to the disease stage and relapsing status. We defined the cutoff values for diagnosis, staging, and relapsing status of these parameters using the receiving operating characteristic curve analysis. Results: For diagnosis, the cutoff values of MPV, Plt, and PCT were 8.49 fL, 32,1000/mm³, and 0.31, respectively. For staging, the cutoff values of MPV and Plt were 9.5 fL and 12 fL, respectively. None of the parameters were associated with relapsing status. Conclusion: This is the first study evaluating Plt-related parameters in Hodgkin’s lymphoma. Further studies including survival analyses will clarify the effect of these parameters on Hodgkin’s lymphoma.en_US
dc.language.isoengen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHodking's Lymphomaen_US
dc.subjectPlateleten_US
dc.subjectMPVen_US
dc.subjectPCTen_US
dc.subjectPDWen_US
dc.titleAre Platelet-related Parameters Predictive of the Prognosis of Hodgkin’s Lymphoma?en_US
dc.typearticleen_US
dc.contributor.departmentALKÜ, Fakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.identifier.volume17en_US
dc.identifier.issue4en_US
dc.identifier.startpage368en_US
dc.identifier.endpage374en_US
dc.relation.journalBakırköy Tıp Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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