The Relationship Between Frontal QRS-T Angle and Premature Ventricular Contraction Burden in Ambulatory 24-Hour Holter
Abstract
Aim: Frequent premature ventricular contractions (PVCs) can cause impaired
ventricular function or dilatation of ventricular cavities. The frontal plane QRS-T
[f(QRS-T)] angle is an indicator of instability in the electrophysiological properties
of the myocardium and is associated with arrhythmias. The present study aimed
to investigate whether f(QRS-T) angle, as a marker of ventricular repolarization
heterogeneity, predicts premature ventricular contraction burden in ambulatory 24-
hour Holter.
Methods: The study included 100 patients. The patients were divided into two groups
as ‘frequent PVC’ and ‘seldom PVC’ according to their PVC burden in 24-hour Holter
monitoring. Laboratory and some ambulatory electrocardiography parameters,
including frontal plane QRS-T angle, were compared between the two groups.
Results: Frontal QRS-T angle (63.34±37.86° vs 23.46±14.29° p<0.001) was found
to be wider in the Frequent PVC group. F(QRS-T) angle of ≥ 34° had a sensitivity of
82.2% and a specificity of 80% in indicating PVC load (AUC: 0.887 (0.824-0.950). In
addition, a positive correlation was found between PVC burden and f(QRS-T) angle
(r:0.429 p<0.001).
Conclusion: The widening of f(QRS-T) angle could perhaps be considered as a
surrogate marker of increased PVC burden in 24-hour Holter monitoring. Measuring
f(QRS-T) angle in 12-lead ECG in patients with PVC may be a warning sign for
increased PVC burden.
Source
Acta Medica AlanyaVolume
6Issue
2URI
https://dergipark.org.tr/tr/download/article-file/2489852https://hdl.handle.net/20.500.12868/1773