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dc.contributor.authorTuncar, Alpay
dc.contributor.authorCander, Başar
dc.contributor.authorKüçükceran, Kadir
dc.contributor.authorYerlikaya, Fatma Hümeyra
dc.date.accessioned2022-10-03T08:31:16Z
dc.date.available2022-10-03T08:31:16Z
dc.date.issued2022en_US
dc.identifier.urihttps://dergipark.org.tr/tr/download/article-file/2427261
dc.identifier.urihttps://hdl.handle.net/20.500.12868/1765
dc.description.abstractAim: This study aimed to demonstrate the diagnostic and prognostic value of NR-2 peptides as a biomarker in acute ischemic stroke and to evaluate their correlation with the Glasgow Coma Scale (GCS) and the National Institutes of Health Stroke Scale (NIHSS). Materials and Methods: The importance of NR-2 peptide level in diagnosis and prognosis in acute stroke was investigated cross-sectional and prospectively. The study included 101 patients, who presented to a tertiary healthcare facility and were diagnosed with acute stroke, and 57 healthy controls. In the whole study population, serum NR-2 peptide levels were measured using the ELISA method. Results: The NR-2 peptide level was 6.32 ± 8.30 in the patient group and 3.91 ± 1.64 in the study group. The NR-2 peptide level was significantly higher in the patient group (p = 0.006). No correlation was detected between NR-2 peptide levels and scores in the GCS or NIHSS. The results indicated that NR-2 was a potential biomarker elevated in the early phase of acute stroke, but had no correlation with the prognosis of acute stroke. Conclusion: Although our data shed light on the use of the NR-2 peptide level as a biomarker in the acute phase in patients with stroke, data are insufficient to predict prognosis. We think that larger, multicenter studies with longer follow-up periods are needed.en_US
dc.language.isoengen_US
dc.relation.isversionof10.30565/medalanya.1116544en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectStrokeen_US
dc.subjectNR-2 peptideen_US
dc.subjectDiagnosisen_US
dc.subjectPrognosisen_US
dc.subjectBiomarkeren_US
dc.titleIs there a relationship between NR-2 antibody peptide level and diagnosis, prognosis and coma scores in acute ischemic stroke?en_US
dc.typearticleen_US
dc.contributor.departmentALKÜen_US
dc.identifier.volume6en_US
dc.identifier.issue2en_US
dc.identifier.startpage145en_US
dc.identifier.endpage160en_US
dc.relation.journalActa Medica Alanyaen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Başka Kurum Yazarıen_US


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