The Effect of Regularly Performed Oderate-Intensity Exercise Program on Thiol/Disulfide Homeostasis, and Ischemia-Modified Albumin
Özet
Aim: Thiol/disulfide homeostasis is an indicator of oxidative stress and antioxidant
capacity. Ischemia-modified albumin (IMA) is an important marker for both oxidative
stress and ischemia. We aimed to evaluate the possible effects of regularly performed
moderate-intensity exercise on thiol/disulfide homeostasis, and IMA levels.
Methods: Sprague Dawley rats were used. The study was composed of an Exercise
group (EG, n=9) and Control group (CG, n=6). A 10-weeks swimming exercise was
performed. Thiol/disulfide homeostasis measurement method was used in this study.
IMA levels were measured by a cobalt-albumin binding method.
Results: In the EG, total thiol levels were significantly higher compared to the CG
(p<0.01). The disulfide/total thiol ratio was lower in the EG compared to the CG
(p<0.01). We observed that there was a slight increase in IMA levels in EG (p=0.18).
This increase was not statistically significant.
Conclusion: Regularly performed moderate-intensity exercise has increased native
and total thiol levels. Increase of thiol levels can prevent oxidative stress. Regularly
performed moderate-intensity exercise programs appear to provide favourable
effects on oxidative stress.
Kaynak
Acta Medica AlanyaCilt
6Sayı
2Bağlantı
https://dergipark.org.tr/tr/download/article-file/2182572https://hdl.handle.net/20.500.12868/1761