| dc.description.abstract | Aim: The most valuable treatment method for coronary artery disease is coronary
artery bypass graft (CABG) surgery. Major cardiovascular and cerebral events
(MACCE) are important challenges, and it is particularly important to reveal possible
risk factors in this regard. In this study, we aimed to investigate the predictive areas
of the prognostic nutritional index (PNI) and the systemic immune inflammation index
(SII) on early postoperatively developing MACCE, in patients who underwent isolated
CABG operation.
Methods: The patients between the ages of 20 and 85 years who underwent
consecutive isolated CABG operation in our clinic between May 15th, 2016, and May
15th, 2020, were included in the study retrospectively. In the postoperative period
(within a month), those who did not develop MACCE were recorded as Group 1, and
those who developed MACCE as Group 2.
Results: A total of 297 consecutive patients were included in the study. Group 1
had 263 patients with a median age of 63 (32-80), Group 2 had 34 patients with a
median age of 70 (36-85) (P=0.008). There was no difference between the groups
in terms of gender, history of cerebrovascular events, smoking, body mass index,
hyperlipidemia, ejection fraction, and chronic obstructive pulmonary disease rates.
As a result of multivariate analysis, advanced age (OR: 1.230 CI 95%: 1.050-1.319
P=0.024), NLR (OR: 1.974 CI 95%: 1.614-3.120, P=0.009), SII (OR: 3.880, CI
95%: 2.690-6.150, P<0.001) and PNI (OR: 2.424, CI 95%: 1.880-3.880, P=0.002)
values were determined as independent predictors for predicting early postoperative
MACCE.
Conclusions: With this study we revealed that SII and PNI values, which are among
the inflammatory parameters and which can be obtained cheaply and easily, may be
good predictors for MACCE emerging after CABG operations | en_US |
