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dc.contributor.authorUğur, Sevcan
dc.contributor.authorKula Atik, Tuğba
dc.date.accessioned2022-09-30T07:24:11Z
dc.date.available2022-09-30T07:24:11Z
dc.date.issued2021en_US
dc.identifier.urihttps://dergipark.org.tr/tr/download/article-file/1825698
dc.identifier.urihttps://hdl.handle.net/20.500.12868/1726
dc.description.abstractAim: In this study we aimed to find the frequency of anti-DFS70 antibodies and DFS pattern in ANA positive individuals and ANA associated rheumatic diseases (AARDs). Methods: In this study, 337 subjects who were evaluated in a rheumatology clinic with prediagnosis of rheumatic diseases with positive ANA test and had concurrent anti-extractable nuclear antigen (anti-ENA) antibodies results were retrospectively analyzed. Clinical diagnosis of patients and demographic characteristics were obtained from the patients' medical records. Results: A total of 337 subjects (305 women, 32 men) were included in this study. The mean age was 49.8 ± 14.2 years. Of the 337 participants, 111 (32.9%) had an IIF-DFS pattern and 226 (67.1%) had a non-DFS pattern. Anti-DFS70 antibodies were positive in 20.1% of individuals. Sixty eight individuals had AARDs. An IIF-DFS pattern was observed in 22.1% and a non-DFS pattern was observed in 77.9% of individuals with AARDs (p <0.05). Anti-DFS70 antibodies were positive in 13.2% of patients with AARDs. The frequency of AARDs was significantly lower in individuals with anti-DFS70 antibodies compared to individuals with other anti-ENAs antibodies (p <0.05). Conclusion: Anti-DFS70 antibodies may be present in patients with AARDs but AARDs are less prevalent in patients who had anti-DFS70 antibodies, compared with patients who had other anti-ENAsen_US
dc.language.isoengen_US
dc.relation.isversionof10.30565/medalanya.952813en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntinuclear antibodies (ANA)en_US
dc.subjectAnti DFS70 antibodyen_US
dc.subjectDFS patteren_US
dc.titleEvaluation of anti-DFS70 antibodies and DFS pattern in ANA positive individuals and ANA Associated Rheumatic Diseasesen_US
dc.typearticleen_US
dc.contributor.departmentALKÜ, Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.identifier.volume5en_US
dc.identifier.issue2en_US
dc.identifier.startpage234en_US
dc.identifier.endpage238en_US
dc.relation.journalActa Medica Alanyaen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US


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