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dc.contributor.authorKorkmaz, Hakan
dc.date.accessioned2022-09-26T11:07:29Z
dc.date.available2022-09-26T11:07:29Z
dc.date.issued2021en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12868/1697
dc.description.abstractAim: To determine the sensitivity and positive predictive value (PPV) of the measurement of parathormone (PTH) in fine needle aspiration (FNA) washout fluid, in the preoperative localization of hyperfunctional parathyroid lesions. Methods: Medical records of patients diagnosed with primary hyperparathyroidism (PHPT) in our clinic between 2016-2020 were retrospectively evaluated. Thirty-six patients with PHPT who underwent preoperative FNA-PTH washout procedure were included in the study. FNA-PTH washout was only performed in patients with negative technetium-99m methoxy isobutyl isonitrile / single photon emission computed tomography (Tc-99m MIBI/SPECT) imaging. It was accepted to be higher than plasma PTH level as positive cut-off value for PTH washout in determining parathyroid lesions. Sensitivity, PPV, false positive, false negative and diagnostic accuracy values of PTH washout were calculated. Results: PTH washout was false positive in 2 cases, false negative in 1 case and true positive in 33 cases. In the discrimination of true parathyroid lesions, the sensitivity of PTH washout was calculated as 97.05%, PPV 94.29% and diagnostic accuracy 91.67%. PTH washout levels correlated positively with plasma PTH and parathyroid lesion volüme (respectively, r=0.347, p=0.041 ve r=0.356, p=0.036). All patients tolerated the FNA-PTH flushing procedure well and no complications developed afterwards. Conclusion: The FNA-PTH washout is a safe and useful method to localise parathyroid lesions in PHPT patients with negative Tc-99m MIBI/SPECT imaging.en_US
dc.language.isoengen_US
dc.relation.isversionofhttps://doi.org/10.30565/medalanya.853038en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectFine needle aspirationen_US
dc.subjectMIBI/SPECT negativeen_US
dc.subjectPrimary hyperparathyroidismen_US
dc.subjectWashouten_US
dc.titleThe diagnostic value of parathormone washout in Tc-99m MIBI negative primary hyperparathyroidism casesen_US
dc.typearticleen_US
dc.contributor.departmentALKÜen_US
dc.identifier.volume5en_US
dc.identifier.issue1en_US
dc.identifier.startpage61en_US
dc.identifier.endpage65en_US
dc.relation.journalActa Medica Alanyaen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Başka Kurum Yazarıen_US


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