The effect of retrograde intrarenal surgery on kidney function in renal stone treatment

Abstract

Aim: In this study, we aimed to evaluate the alteration in renal function by analyzing the estimated glomerular filtration rate after Retrograde Intrarenal Surgery, and present the factors which have an impact on alteration. Methods: We analyzed 88 patients who underwent RIRS for renal stones between May 2018 and February 2019, prospectively. Estimated glomerular filtration rate was calculated by modification of diet in renal disease (MDRD) formula preoperatively, on the first postoperative day, on the first postoperative month and the third postoperative month. All data was recorded on the follow-up form. All procedures were performed under general anesthesia. Results: The stone-free rate of the study was 79.5%. Preoperative eGFR was 99.86 mL/min/1.73m2 for the study group. The eGFR was calculated 101.80 mL/min/1.73m2 on the first postoperative day and 111.66 mL/min/1.73m2 on the third-month follow-up. The change in eGFR was 1.94 mL/min/1.73m2 in the early period and 11.8 mL/min/1.73m2 in the long-term follow-up period. There was a statistically significant improvement in eGFR in the long-term follow-up period than the early period when compared to preoperative renal function. Conclusion: On the contrary of former stone removal modalities, RIRS can stabilize postoperative kidney function. It may even help improve postoperative kidney function in patients with preoperative renal dysfunction. Urologists may keep in mind the RIRS option in patients with this condition