Seasonal variation of immune hemolytic anemia
Abstract
Aim: Immune hemolytic anemia is an autoimmune disease that is related to autoantibodies against erythrocytes. Such antibodies appear for a variety of reasons such as
hematologic and oncologic malignancies, infections, and connective tissue diseases
but in many cases, a true etiologic agent has not been discovered. Many hematologic
as well as rheumatologic disorders have seasonal variations but there have not been
many studies evaluating the possibility of seasonal variation of immune hemolytic
anemia.
Methods: It was investigated whether the patients with immune hemolytic anemia
who were diagnosed and followed in the hematology outpatient and inpatient clinic
of Suleyman Demirel University from 2002 to 2018 had a significant seasonality. We
also evaluated whether there was any seasonality relationship between gender and
beginning of the hemolytic attacks.
Results: There was no significant difference when seasons were grouped as spring,
summer, autumn and winter, according to gender (p = 0,122). The evaluation of seasons in two groups as autumn-winter and spring-Summer revealed that male patients
tended to suffer immune hemolytic anemia in autumn-winter, whereas females, significantly, tend to contract the disease in spring-Summer (p=0,046).
Conclusion: Immune hemolytic anemia had significant seasonality pattern depending on gender. More prospective studies are needed to support these findings in this
study
Source
Acta Medica AlanyaVolume
5Issue
1URI
https://dergipark.org.tr/en/pub/medalanya/issue/61925/804346https://hdl.handle.net/20.500.12868/1693