The relationship between procalcitonin, D-dimer, ferritin, troponin and lactate levels with COVID-19
Abstract
Aim: Coronavirus disease-2019 patients may experience an increase in inflammation or clotting disorders. It is believed that some biomarkers can be decisive in decision to hospitalize. Our aim in this study was to investigate the relationship between
serum procalcitonin, troponin, D-dimer, ferritin and lactate levels, and Coronavirus
disease-2019.
Methods: Patients suspected of suffering from the Coronavirus disease-2019 and
whose serum biochemistry and blood gas tests were performed, were included in the
study. The relationships between the blood parameters of the patients with negative
or positive Polymerase Chain Reaction test results, and those who were hospitalized
or non-hospitalized, were examined.
Results: Out of a total of 452 patients, 244 (54%) were male and 208 (46%) were
female. There was a statistically significant difference between polymerase chain
reaction test positive and test negative groups in terms of procalcitonin, D-dimer,
lactate and troponin levels (p˂0.005). There was no statistically significant difference
between hospitalized and non hospitalized patient in terms of ferritin (p=0.224). However, there was a significant difference in terms of procalcitonin, D-dimer and troponin
levels (p˂0.005).
Conclusion: Our results revealed that high serum procalcitonin, D-dimer, lactate
and troponin levels are associated with the decision to hospitalize Coronavirus disease-2019 patients, whereas ferritin levels played no such role.