Güncel Gönderiler: Araştırma Çıktıları (TR Dizin / Web of Science / Scopus / PubMed)
Toplam kayıt 1535, listelenen: 1321-1340
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Selenium enhances TRPA1 channel-mediated activity of temozolomide in SH-SY5Y neuroblastoma cells
(Springer, 2020)Purpose Neuroblastoma is a malignant solid tumor that originates from the sympathetic nervous system in early childhood. Temozolomide is used for treatment in high-risk groups with low treatment response of neuroblastomas. ... -
The effect of intracerebral structure volumes on idiopathic intracranial hypertension
(Lippincott Williams & Wilkins, 2021)Background This aim of this study was to assess the effect of idiopathic intracranial hypertension (IIH) in the development of intracranial hypertension by measuring patients' cerebrospinal fluid (CSF), brain, and segment ... -
Selenium enhances TRPA1 channel-mediated activity of temozolomide in SH-SY5Y neuroblastoma cells (vol 21, pg 541, 2020)
(Springer, 2020)[No abstract available] -
Protective effects of N-acetyl cysteine against paclitaxel-induced cardiotoxicity through modulation of transient receptor potential melastatin 2 channels
(Gazi Univ, Fac Med, 2019)Aim : In our study, we investigated the paclitaxel induced cardiotoxicity and alterations in Ca2+ influx, oxidative stress and apoptosis through transient receptor potential melastatin 2 (TRPM2) channels and modulator role ... -
Using action research based on the predict-observe-explain strategy for teaching enzymes
(Mehmet Tekerek, 2016)The science laboratory course is one of the important courses that preservice science students take in their science education programs. The purpose of this study is to investigate the impact of an action research based ... -
Synergic and comparative effect of 5-fluorouracil and leucoverin on breast and colon cancer cells through TRPM2 channels
(Comenius Univ, 2018)OBJECTIVES: We aimed to reveal the role of 5-fluorouracil (5-FU) and Leucovorin (LV) along with transient receptor potential protein melastatin 2 (TRPM2) channels in breast and colon cancer cells during the treatment ... -
The effect of melatonin on digoxin-induced cardiac damage in cardiomyocytes
(Comenius Univ, 2019)OBJECTIVES: Digoxin is a cardiac glycoside which is widely used in cardiovascular medicine. Oxidative stress, as well as intracellular Ca2+ overload, plays an important role in digoxin toxicity. Transient receptor potential ... -
The role of selenium in bevacizumab induced cardiotoxicity
(Comenius Univ, 2019)OBJECTIVE: We investigated the role of selenium in bevacizumab induced cardiotoxicity and involvement of transient receptor potential vanilloid 1 (TRPV1) channels in cardiomyocytes. MATERIALS AND METHODS: All cells (Human ... -
LLLT enhance cyclophosphamide induced TRPM2 channel activation in human colon cancer cells
(Comenius Univ, 2020)AIM: Transient receptor potential (TRP) channels expression is enhanced significantly in colon cancer cells and Low Lever Laser Treatment (LLLT), is known to have effects and is used clinically in the treatment ofmany ... -
Mathematical modeling of packed bed and microwave drying of enriched couscous
(Springer, 2018)In this study, the drying kinetics and modeling of enriched couscous with two different compositions (A and B) were carried out by using packed bed (60 and 80 A degrees C) and microwave (180 and 360 W) drying techniques. ... -
The effects of carvacrol on oxidative stress parameters and adoptosis process via TRPA1 channels in neuroblastoma cells
(Polskie Towarzystwo Farmaceutyczne, 2019)Objectives: This study is a preliminary study to investigate the effects of carvacrol (CRV) obtained from thyme on the apoptosis process in neuroblastoma cells. Methods: In this study, seven groups were designed as control, ... -
Effects of homocysteine and memantine on oxidative stress related TRP cation channels inin-vitromodel of Alzheimer's disease
(Taylor & Francis Ltd, 2020)Memantine (MEM) has been used to treat patients with Alzheimer' disease though inhibition of reactive oxygen species (ROS), Ca(2+)entry and glutamate receptor. The Ca(2+)permeable TRPA1, TRPM2 and TRPV1 channels are activated ... -
Paracetamol alters empathy scores in healthy and headache subjects: Functional MRI correlates
(Elsevier Sci Ltd, 2020)Introduction: Although previous evidence suggest that paracetamol decreases psychological reactivity in healthy subjects, there is still no confirmed correlation between the empathy scores and brain activity in healthy and ... -
Numerical investigation of the effects of geometric structure of microchannel heat sink on flow characteristics and heat transfer performance
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2019)A numerical study was performed to investigate the thermal-hydraulic performance of different microchannel heat sink (MCHS) designs for cooling channels in a lithium-ion battery including various geometric modifications. ... -
Synthesis, characterization, and application of transition metals (Ni, Zr, and Fe) doped TiO2 photoelectrodes for dye-sensitized solar cells
(Elsevier, 2020)In this paper, we present the synthesis of different metal-doped TiO2 compounds (pure TiO2, Fe doped TiO2 (FexTi1-xO2), Ni doped TiO2 (NixTi1-xO2), Zr doped TiO2 (ZrxTi1-xO2)) thin films in order to improve the performance ... -
Bubble-based stabilized finite element methods for time-dependent convection-diffusion-reaction problems
(Wiley, 2016)In this paper, we propose a numerical algorithm for time-dependent convection-diffusion-reaction problems and compare its performance with the well-known numerical methods in the literature. Time discretization is performed ... -
Wound healing effects of methanol extract of Laurocerasus officinalis roem
(Taylor & Francis Ltd, 2019)Laurocerasus officinalis Roem. (syn: Prunus laurocerasus L.) is a member of Rosaceae family. We investigated the antimicrobial and antioxidant activity of L. officinalis Roem in wound healing both in vivo and in vitro using ... -
Effects of homocysteine and memantine on oxidative stress related TRP cation channels in in-vitro model of alzheimer's disease
(Wiley, 2018)[No abstract available] -
Calorie restriction protects against apoptosis, mitochondrial oxidative stress and increased calcium signaling through inhibition of TRPV1 channel in the hippocampus and dorsal root ganglion of rats
(Springer/Plenum Publishers, 2018)The TRPV1 channel is activated in neurons by capsaicin, oxidative stress, acidic pH and heat factors, and these factors are attenuated by the antioxidant role of calorie restriction (CR). Hence, we investigated the hypothesis ... -
Biological behaviors of muscarinic receptors in mesenchymal stem cells derived from human placenta and bone marrow
(Mashhad Univ Med Sciences, 2020)Objective(s): Cells perform their functional activities by communicating with each other through endogenous substances and receptors. Post-translation, stem cells function properly in new host tissue by carrying specific ...
