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Agomelatine could prevent brain and cerebellum injury against LPS-induced neuroinflammation in rats
Savran, Meltem Karadeniz; Aslankoç, Rahime; Özmen, Özlem; Erzurumlu, Yalçın; Savas, Hasan Basri; Temel, Esra Nurlu; Bortepe, S. (Academic Press Ltd- Elsevier Science Ltd, 2020)Sepsis, systemic hyper-inflammatory immune response, causes the increase of morbidity and mortality rates due to multi-organ diseases such as neurotoxicity. Lipopolysaccharide (LPS) induces inflammation, oxidative stress ... -
Ameliorative effects of pregabalin on LPS induced endothelial and cardiac toxicity
Aşçı, Halil; Özmen, Özlem; Erzurumlu, Yalçın; Savaş, Hasan Basri; Temel, Esra Nurlu; İçten, Pelin; Hasseyid, N. (Taylor & Francis Ltd, 2020)We investigated the antioxidant, anti-inflammatory and anti-apoptotic effects of pregabalin (PREG) on lipopolysaccharide (LPS) induced sepsis related cardiotoxicity via NF-k beta pathways. We used 24 female Wistar albino ...
