Yazar "Nazıroğlu, Mustafa" için listeleme
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Calorie restriction protects against apoptosis, mitochondrial oxidative stress and increased calcium signaling through inhibition of TRPV1 channel in the hippocampus and dorsal root ganglion of rats
Gültekin, Fatih; Nazıroğlu, Mustafa; Savaş, Hasan Basri; Çiğ, Bilal (Springer/Plenum Publishers, 2018)The TRPV1 channel is activated in neurons by capsaicin, oxidative stress, acidic pH and heat factors, and these factors are attenuated by the antioxidant role of calorie restriction (CR). Hence, we investigated the hypothesis ... -
Clostridium botulinumneurotoxin A induces apoptosis and mitochondrial oxidative stress via activation of TRPM2 channel signaling pathway in neuroblastoma and glioblastoma tumor cells
Akpınar, Orhan; Özşimşek, Ahmet; Güzel, Mustafa; Nazıroğlu, Mustafa (Taylor & Francis Ltd, 2020)Background TheClostridium botulinumneurotoxin A (BTX) is a polypeptide produced by the bacteriumClostridium botulinum. In addition to the therapeutic actions of BTX against pain and neuromuscular disorders, it is acted as ... -
Effects of homocysteine and memantine on oxidative stress related TRP cation channels in in-vitro model of alzheimer's disease
Övey, İshak Suat; Nazıroğlu, Mustafa (Wiley, 2018)[No abstract available] -
Effects of homocysteine and memantine on oxidative stress related TRP cation channels inin-vitromodel of Alzheimer's disease
Övey, İshak Suat; Nazıroğlu, Mustafa (Taylor & Francis Ltd, 2020)Memantine (MEM) has been used to treat patients with Alzheimer' disease though inhibition of reactive oxygen species (ROS), Ca(2+)entry and glutamate receptor. The Ca(2+)permeable TRPA1, TRPM2 and TRPV1 channels are activated ... -
Zoledronic Acid, Bevacizumab and Dexamethasone-induced Apoptosis, Mitochondrial Oxidative stress, and Calcium signaling are decreased in human Osteoblast-like cell line by Selenium treatment
Yazıcı,Tayfun; Koçer, Gülperi; Nazıroğlu, Mustafa; Övey, İshak Suat; Öz, Ahmi (Humana Press Inc, 2018)Increased intracellular free calcium ion (Ca2+) concentration induces excessive oxidative stress and apoptosis. Medical procedures such as zoledronic acid (Zol), bevacizumab (Bev), and dexamethasone (Dex) are usually used ...
