Yazar "Küçüksayan, Ertan" için listeleme
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Effects of somatostatin and vitamin C on the fatty acid profile of breast cancer cell membranes
Hanikoğlu, Ayşegüll; Küçüksayan, Ertan; Hanikoğlu, Ferhat; Özben, Tomris; Menounou, Georgia; Sansone, Anna; Ferreri, Carla (Bentham Science Publ Ltd, 2019)Background: Vitamin C (Vit C) is an important physiological antioxidant with growing applications in cancer. Somatostatin (SST) is a natural peptide with growth inhibitory effect in several mammary cancer models. Objective: ... -
Effects of somatostatin, curcumin, and quercetin on the fatty acid profile of breast cancer cell membranes
Hanikoğlu, Ayşegül; Küçüksayan, Ertan; Hanikoğlu, Ferhat; Özben, Tomris; Menounou, Georgia; Sansone, Anna; Ferreri, Carla (Canadian Science Publishing, 2020)Breast cancer is a worldwide commonly found malignancy in women and effective treatment is regarded as a huge clinical challenge even in the presence of several treatment options. Extensive literature is available demonstrating ... -
Histopathological and biochemical assessment of a novel diagnostic method for ovarian torsion
Özekinci, Murat; Küçüksayan, Ertan; Erdoğan, Gülgün; Aslan, Mutay; Peştereli, Elif; Canpolat, Murat; Sırcan Küçüksayan, Aslınur (Taylor & Francis Ltd, 2020)Ovarian torsion is agynecologic emergency that affects females of all ages. Early diagnosis is important to preserve ovarian function. The false positive rate for sonographic diagnosis of ovarian torsion is 50%; therefore, ... -
Melanoma hücrelerinde epoksomisinin indüklediği apoptozis sürecinde gerçekleşen erken spektral değişikliklerin belirlenmesi
Amaç: Hücrelerde apoptozis sürecinde meydana gelen spektral değişikliklerin belirlenmesi yeni tedavi ve ilaç araştırmalarına önemli bilgiler sağlayabilir. Apoptotik hücreler, hücre küçülmesi ve parçalanmasına yol açan bir ... -
A new low-cost and portable optical device for real-time assessment of tissue microcirculation
Sırcan Küçüksayan, Aslınur; Sırcan, Ahmet Kürşad; Küçüksayan, Ertan (Ieee, 2019)In this work, we have developed a new portable optical device to assess tissue microcirculation. Our system is based on the idea that we can calculate tissue oxygen saturation by analyzing tissue interaction with light at ... -
Plasma thiol/disulphide homeostasis changes in patients with relapsing-remitting multiple sclerosis
Özben, Serkan; Küçüksayan, Ertan; Köseoğlu, Mesrure; Erel, Özcan; Neşelioğlu, Salim; Özben, Tomris (2021)Background: Multiple sclerosis (MS) is a neuroinflammatory disease and inflammation and oxidative stress play important roles in its pathology. Thiol/disulphide homeostasis (TDH) is a special oxidative stress biomarker ... -
Real-Time Detection of Doxorubicin-InducedApoptosis in Breast Cancer Cells Using the BackReflection Spectroscopy
Apoptosis detection methods cause the cell culture medium to be physically or chemically affected. In addition, these methods have disadvantages such as cost and cell losses. The aim of this study is to develop a method ... -
A review on melatonin’s effects in cancer: Potential mechanisms
Hanikoğlu, Ayşegül; Küçüksayan, Ertan; Akduman, Rana; Özben, Tomris (Bentham Science Publishers B.V., 2018)This systematic review aims to elucidate the role of melatonin (N-acetyl-5-metoxy-tryptamine) (MLT) in the prevention and treatment of cancer. MLT is a pineal gland secretory product, an evolutionarily highly conserved ... -
Sapienic Acid Metabolism Influences Membrane Plasticity and Protein Signaling in Breast Cancer Cell Lines
Küçüksayan, Ertan; Sansone, Anna; Chatgilialoglu, Chryssostomos; Özben, Tomris; Tekeli, Demet; Talibova, Günel; Ferreri, Carla (2022)Abstract: The importance of sapienic acid (6c-16:1), a monounsaturated fatty acid of the n-10 family formed from palmitic acid by delta-6 desaturase, and of its metabolism to 8c-18:1 and sebaleic acid (5c,8c-18:2) has ... -
Sapienik asidin melanoma hücrelerinde MAPK yolağına etkisinin araştırılması
Soyuğur, Merve (Alanya Alaaddin Keykubat Üniversitesi / Lisansüstü Eğitim Enstitüsü / Moleküler Tıp Ana Bilim Dalı / Moleküler Tıp Bilim Dalı, 2021)Agresif bir cilt kanseri türü olan melanoma, morbidite ve mortalitenin önemli bir nedeni olup insidansı dünya çapında gittikçe artmaktadır. Kanser hücrelerindeki sinyal yolaklarının aydınlatılması uygulanacak tedavilerin ...
