Yazar "Özmen, Özlem" için listeleme
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Agomelatine could prevent brain and cerebellum injury against LPS-induced neuroinflammation in rats
Savran, Meltem Karadeniz; Aslankoç, Rahime; Özmen, Özlem; Erzurumlu, Yalçın; Savas, Hasan Basri; Temel, Esra Nurlu; Bortepe, S. (Academic Press Ltd- Elsevier Science Ltd, 2020)Sepsis, systemic hyper-inflammatory immune response, causes the increase of morbidity and mortality rates due to multi-organ diseases such as neurotoxicity. Lipopolysaccharide (LPS) induces inflammation, oxidative stress ... -
Ameliorative effects of pregabalin on LPS induced endothelial and cardiac toxicity
Aşçı, Halil; Özmen, Özlem; Erzurumlu, Yalçın; Savaş, Hasan Basri; Temel, Esra Nurlu; İçten, Pelin; Hasseyid, N. (Taylor & Francis Ltd, 2020)We investigated the antioxidant, anti-inflammatory and anti-apoptotic effects of pregabalin (PREG) on lipopolysaccharide (LPS) induced sepsis related cardiotoxicity via NF-k beta pathways. We used 24 female Wistar albino ... -
The differentiation of metastatic mediastinal lymph nodes From benign hypermetabolic lesions
Bulut, Sertan; Çelik, Deniz; Karamanlı, Harun; Aktaş, Zafer; Özmen, Özlem; Ertürk, Hakan; Gürçay, Nesrin; Biber, Çiğdem (2022)Background Anthracosis may cause a positron emission tomography/computed tomography (PET/CT) false positivity in mediastinal and hilar lymph nodes. We aimed to evaluate the radiological features and the maximum standardized ... -
Effects of LDD and CAPE Administration on Total Antioxidant and Total Oxidant Levels in Experimental Periodontitis Model of Rat Brain
Aim: Observing the effects of caffeic acid phenethyl ester (CAPE) and/or low dose doxycycline (LDD) on total antioxidant and oxidant status of brain in experimental periodontitis is the purpose of the study. Methods: ... -
The impact of prophylactic lacosamide on LPS-induced neuroinflammation in aged rats
Savran, Mehtap; Özmen, Özlem; Erzurumlu, Yalçın; Savaş, Hasri Basri; Aşçı, S.; Kaynak, M. (Springer/Plenum Publishers, 2019)Sepsis-induced central nervous system damage is called sepsis-associated encephalopathy (SAE). In addition to neuroinflammation, oxidative stress and apoptosis act in the development of SAE. In the current study, we evaluated ... -
Melatonin protects the heart and endothelium against high fructose corn syrup consumption-induced cardiovascular toxicity via SIRT-1 signaling
Savran, Mehtap; Aşçı, Halil; Özmen, Özlem; Erzurumlu, Yalçın; Savaş, Hasan Basri; Sönmez, Yasin; Şahin, Yasemin (Sage Publications Ltd, 2019)High fructose corn syrup (HFCS) has been shown to cause cardiovascular toxicity via oxidative stress and inflammation. The aim of this study is to demonstrate the protective effects of melatonin (MLT) against HFCS-induced ... -
Sıçanlarda indometazin ile indüklenmiş peptik ülser modelinde tarantula cubensis ekstraktının gastroprotektif etkisi
Çankara, Fatma Nihan; Özmen, Özlem; Savaş, Hasan Basri; Şahin, Yasemin; Günaydın, Caner (Alanya Alaaddin Keykubat Üniversitesi, 2020)Amaç: Gastrik ülser, endüstrileşmiş dünyada çeşitli faktörler nedeniyle en sık görülen gastrointestinal hastalıktır. Bununla birlikte mide ülseri, gastrointestinal sağlığın korunması için genellikle tercih edilen proton ...
