Yazar "Savaş, Hasan Basri" için PubMed İndeksli Yayınlar Koleksiyonu listeleme
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Ameliorative effects of pregabalin on LPS induced endothelial and cardiac toxicity
Aşçı, Halil; Özmen, Özlem; Erzurumlu, Yalçın; Savaş, Hasan Basri; Temel, Esra Nurlu; İçten, Pelin; Hasseyid, N. (Taylor & Francis Ltd, 2020)We investigated the antioxidant, anti-inflammatory and anti-apoptotic effects of pregabalin (PREG) on lipopolysaccharide (LPS) induced sepsis related cardiotoxicity via NF-k beta pathways. We used 24 female Wistar albino ... -
Calorie restriction protects against apoptosis, mitochondrial oxidative stress and increased calcium signaling through inhibition of TRPV1 channel in the hippocampus and dorsal root ganglion of rats
Gültekin, Fatih; Nazıroğlu, Mustafa; Savaş, Hasan Basri; Çiğ, Bilal (Springer/Plenum Publishers, 2018)The TRPV1 channel is activated in neurons by capsaicin, oxidative stress, acidic pH and heat factors, and these factors are attenuated by the antioxidant role of calorie restriction (CR). Hence, we investigated the hypothesis ... -
Circulation levels of acute phase proteins pentraxin 3 and serum amyloid a in atherosclerosis have correlations with periodontal inflamed surface area
Temelli, Başak; Yetkin Ay, Zuhal; Savaş, Hasan Basri; Aksoy, Fatih; Kumbul Doğuç, Duygu; Uskun, Ersin; Varol, Ercan (Univ Sao Paulo Fac Odontologia Bauru, 2018)Objectives: One of the plausible mechanisms in the relationship between periodontitis and coronary artery disease (CAD) is the systemic inflammatory burden comprised of circulating cytokines/mediators related to periodontitis. ... -
Enzymatic behavior of laccase following interaction with gamma-CD and immobilization into PCL nanofibers
Canbolat, Mehmet Fatih; Savaş, Hasan Basri; Gültekin, Fatih (Academic Press Inc Elsevier Science, 2017)This study examines the effects of CD use on enzymatic activity, following enzyme immobilization into nanofibers. There is almost no research available on the change in enzyme activity following interaction with cyclodextrin ... -
Food additives and microbiota
The use of food additives in food production is inevitable in this modern world. Although only a safe amount of food additives is approved, their safety has always been questioned. To our knowledge, the effects of food ... -
Melatonin protects the heart and endothelium against high fructose corn syrup consumption-induced cardiovascular toxicity via SIRT-1 signaling
Savran, Mehtap; Aşçı, Halil; Özmen, Özlem; Erzurumlu, Yalçın; Savaş, Hasan Basri; Sönmez, Yasin; Şahin, Yasemin (Sage Publications Ltd, 2019)High fructose corn syrup (HFCS) has been shown to cause cardiovascular toxicity via oxidative stress and inflammation. The aim of this study is to demonstrate the protective effects of melatonin (MLT) against HFCS-induced ... -
Positive effects of meal frequency and calorie restriction on antioxidant systems in rats
Savaş, Hasan Basri; Gültekin, Fatih; Çiriş, İbrahim Metin (Kare Publ, 2017)OBJECTIVE: In living organisms, there is a balance between the oxidant and antioxidant systems. Reactive products continuously formed by exogenous and endogenous sources are rendered harmless by the antioxidant system. ...