Antibacterial effects of leukocyte and platelet-rich fibrin against Escherichia coli and Enterococcus faecalis

Abstract

Aim: The main goal of this research was to explore the in-vitro antibacterial characteristics of leukocyte and platelet-rich fibrin (L-PRF) against Escherichia coli (E. Coli) and Enterococcus faecalis (E. Faecalis). Materials and methods: The study was conducted on 21 patients (10 females, 11 males, age range 21-32 years). L-PRF was prepared from the participants’ own blood. Antibacterial activity of L-PRF against E. coli and E. faecalis ATCC standard strains was analyzed using the Kirby Bauer disk diffusion method. Results: The inhibition zones with PRF had not been detected even though the results obtained using control discs were in accordance with the expectations. Conclusion: L-PRF demonstrated no inhibition zone against E. coli and E. faecalis.