Yazar "Savaş, Hasan Basri" için WoS İndeksli Yayınlar Koleksiyonu listeleme
-
Ameliorative effects of pregabalin on LPS induced endothelial and cardiac toxicity
Aşçı, Halil; Özmen, Özlem; Erzurumlu, Yalçın; Savaş, Hasan Basri; Temel, Esra Nurlu; İçten, Pelin; Hasseyid, N. (Taylor & Francis Ltd, 2020)We investigated the antioxidant, anti-inflammatory and anti-apoptotic effects of pregabalin (PREG) on lipopolysaccharide (LPS) induced sepsis related cardiotoxicity via NF-k beta pathways. We used 24 female Wistar albino ... -
Calorie restriction protects against apoptosis, mitochondrial oxidative stress and increased calcium signaling through inhibition of TRPV1 channel in the hippocampus and dorsal root ganglion of rats
Gültekin, Fatih; Nazıroğlu, Mustafa; Savaş, Hasan Basri; Çiğ, Bilal (Springer/Plenum Publishers, 2018)The TRPV1 channel is activated in neurons by capsaicin, oxidative stress, acidic pH and heat factors, and these factors are attenuated by the antioxidant role of calorie restriction (CR). Hence, we investigated the hypothesis ... -
Cilostazol induces angiogenesis and regulates oxidative stress in a dose-dependent manner: A chorioallantoic membrane study
ABSTRACT Background: In this study, we aimed to investigate the effects of cilostazol on angiogenesis and oxidative stress using the chorioallantoic membrane model. Methods: In this experimental study, the Ross 308 ... -
Circulation levels of acute phase proteins pentraxin 3 and serum amyloid a in atherosclerosis have correlations with periodontal inflamed surface area
Temelli, Başak; Yetkin Ay, Zuhal; Savaş, Hasan Basri; Aksoy, Fatih; Kumbul Doğuç, Duygu; Uskun, Ersin; Varol, Ercan (Univ Sao Paulo Fac Odontologia Bauru, 2018)Objectives: One of the plausible mechanisms in the relationship between periodontitis and coronary artery disease (CAD) is the systemic inflammatory burden comprised of circulating cytokines/mediators related to periodontitis. ... -
Effects of nutrition style on neuro-behavior
Savaş, Hasan Basri; Gültekin, Fatih; Doğuç, Duygu Kumbul (Allied Acad, 2017)Objective: The effects of meal frequency and caloric restriction on spatial memory based on hippocampus in rats were examined in our study. Materials and methods: As a result of a four-weeks pilot study amount of food and ... -
Enzymatic behavior of laccase following interaction with gamma-CD and immobilization into PCL nanofibers
Canbolat, Mehmet Fatih; Savaş, Hasan Basri; Gültekin, Fatih (Academic Press Inc Elsevier Science, 2017)This study examines the effects of CD use on enzymatic activity, following enzyme immobilization into nanofibers. There is almost no research available on the change in enzyme activity following interaction with cyclodextrin ... -
Food additives and microbiota
The use of food additives in food production is inevitable in this modern world. Although only a safe amount of food additives is approved, their safety has always been questioned. To our knowledge, the effects of food ... -
Improved catalytic activity by catalase immobilization using -cyclodextrin and electrospun PCL nanofibers
Canbolat, M. Fatih; Savaş, Hasan Basri; Gültekin, Fatih (Wiley, 2017)Nanofibrous structures are promising for biocatalyst immobilization due to their large surface area which facilitates the enzyme attachment, stability, ease of separation, and fine porous structure. There is limited research ... -
A Mathematical modelling approach in the spread of the novel 2019 Coronavirus SARS-CoV-2 (COVID-19) pandemic
Çakır, Zafer; Savaş, Hasan Basri (Modestum Ltd, 2020)The novel 2019 coronavirus, SARS-CoV-2 (COVID-19), emerged towards the end of 2019 in the city of Wuhan in the province of Hubei in the People's Republic of China, and it has spread to the entire world very fast and in a ... -
Melatonin protects the heart and endothelium against high fructose corn syrup consumption-induced cardiovascular toxicity via SIRT-1 signaling
Savran, Mehtap; Aşçı, Halil; Özmen, Özlem; Erzurumlu, Yalçın; Savaş, Hasan Basri; Sönmez, Yasin; Şahin, Yasemin (Sage Publications Ltd, 2019)High fructose corn syrup (HFCS) has been shown to cause cardiovascular toxicity via oxidative stress and inflammation. The aim of this study is to demonstrate the protective effects of melatonin (MLT) against HFCS-induced ... -
Positive effects of meal frequency and calorie restriction on antioxidant systems in rats
Savaş, Hasan Basri; Gültekin, Fatih; Çiriş, İbrahim Metin (Kare Publ, 2017)OBJECTIVE: In living organisms, there is a balance between the oxidant and antioxidant systems. Reactive products continuously formed by exogenous and endogenous sources are rendered harmless by the antioxidant system. ... -
Predictive value of oxidant and antioxidant status for contrast-induced nephropathy after percutaneous coronary intervention for ST-segment elevation myocardial infarction
Background: Contrast-induced nephropathy (CIN) is a life-threatening complication after primary percutaneous coronary intervention (p-PCI). Oxidative stress and inflammation may play an important role in the development ... -
Salivary glands of fetuses are adversely affected by artificial food colorings in rats
Savaş, Hasan Basri; Gültekin, Fatih; Başak, Kayhan; Aylak, Firdevs; Doğuç, Duygu Kumbul; Gürdal, Osman (2021)OBJECTIVE: Artificial food colorings, as types of food additives, are widely used at present in daily life. We aimed to investigate the effects of exposure to artificial food colorings during the intrauterine period on the ... -
Thiol disulfide balance oxidative stress and paraoxonase 1 activities in children and adolescents aged 6-16 Years with specific learning disorders
Savaş, Hasan Basri; Sayar, Ersin; Kara Tayfun (2021)Introduction: Specific learning disorders (SLD) are some of the most common neurodevelopmental disorders. The aim of this study is to determine the potential relationship between children with SLD and zinc, copper, paraoxonase ...