Yazar "Övey, İshak Suat" için WoS İndeksli Yayınlar Koleksiyonu listeleme
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Apoptotic efficiency of capecitabine and 5-fluorouracil on human cancer cells through TRPV1 channels
Övey, İshak Suat; Güler, Yılmaz (Natl Inst Science Communication-Niscair, 2020)The expression of transient receptor potential protein channels increases intensively colon and breast cancer cells. We aimed to reveal the role of 5-fluorouracil (5FU) and capecitabine along with Transient Receptor Potential ... -
The effect of melatonin on digoxin-induced cardiac damage in cardiomyocytes
Övey, İshak Suat; Öncel, Can Ramazan (Comenius Univ, 2019)OBJECTIVES: Digoxin is a cardiac glycoside which is widely used in cardiovascular medicine. Oxidative stress, as well as intracellular Ca2+ overload, plays an important role in digoxin toxicity. Transient receptor potential ... -
The effects of carvacrol on oxidative stress parameters and adoptosis process via TRPA1 channels in neuroblastoma cells
Günal, Mehmet Yalçın; Övey, İshak Suat (Polskie Towarzystwo Farmaceutyczne, 2019)Objectives: This study is a preliminary study to investigate the effects of carvacrol (CRV) obtained from thyme on the apoptosis process in neuroblastoma cells. Methods: In this study, seven groups were designed as control, ... -
Effects of homocysteine and memantine on oxidative stress related TRP cation channels in in-vitro model of alzheimer's disease
Övey, İshak Suat; Nazıroğlu, Mustafa (Wiley, 2018)[No abstract available] -
Effects of homocysteine and memantine on oxidative stress related TRP cation channels inin-vitromodel of Alzheimer's disease
Övey, İshak Suat; Nazıroğlu, Mustafa (Taylor & Francis Ltd, 2020)Memantine (MEM) has been used to treat patients with Alzheimer' disease though inhibition of reactive oxygen species (ROS), Ca(2+)entry and glutamate receptor. The Ca(2+)permeable TRPA1, TRPM2 and TRPV1 channels are activated ... -
LLLT enhance cyclophosphamide induced TRPM2 channel activation in human colon cancer cells
Güler, Yılmaz; Övey, İshak Suat (Comenius Univ, 2020)AIM: Transient receptor potential (TRP) channels expression is enhanced significantly in colon cancer cells and Low Lever Laser Treatment (LLLT), is known to have effects and is used clinically in the treatment ofmany ... -
Protective effects of N-acetyl cysteine against paclitaxel-induced cardiotoxicity through modulation of transient receptor potential melastatin 2 channels
Öncel, Can Ramazan; Övey, İshak Suat (Gazi Univ, Fac Med, 2019)Aim : In our study, we investigated the paclitaxel induced cardiotoxicity and alterations in Ca2+ influx, oxidative stress and apoptosis through transient receptor potential melastatin 2 (TRPM2) channels and modulator role ... -
The role of selenium in bevacizumab induced cardiotoxicity
Öncel, Can Ramazan; Övey, İshak Suat (Comenius Univ, 2019)OBJECTIVE: We investigated the role of selenium in bevacizumab induced cardiotoxicity and involvement of transient receptor potential vanilloid 1 (TRPV1) channels in cardiomyocytes. MATERIALS AND METHODS: All cells (Human ... -
Selenium enhances TRPA1 channel-mediated activity of temozolomide in SH-SY5Y neuroblastoma cells
Özkal, Birol; Övey, İshak Suat (Springer, 2020)Purpose Neuroblastoma is a malignant solid tumor that originates from the sympathetic nervous system in early childhood. Temozolomide is used for treatment in high-risk groups with low treatment response of neuroblastomas. ... -
Selenium enhances TRPA1 channel-mediated activity of temozolomide in SH-SY5Y neuroblastoma cells (vol 21, pg 541, 2020)
Özkal, Birol; Övey, İshak Suat (Springer, 2020)[No abstract available] -
Synergic and comparative effect of 5-fluorouracil and leucoverin on breast and colon cancer cells through TRPM2 channels
Güler, Yılmaz; Övey, İshak Suat (Comenius Univ, 2018)OBJECTIVES: We aimed to reveal the role of 5-fluorouracil (5-FU) and Leucovorin (LV) along with transient receptor potential protein melastatin 2 (TRPM2) channels in breast and colon cancer cells during the treatment ... -
Zoledronic Acid, Bevacizumab and Dexamethasone-induced Apoptosis, Mitochondrial Oxidative stress, and Calcium signaling are decreased in human Osteoblast-like cell line by Selenium treatment
Yazıcı,Tayfun; Koçer, Gülperi; Nazıroğlu, Mustafa; Övey, İshak Suat; Öz, Ahmi (Humana Press Inc, 2018)Increased intracellular free calcium ion (Ca2+) concentration induces excessive oxidative stress and apoptosis. Medical procedures such as zoledronic acid (Zol), bevacizumab (Bev), and dexamethasone (Dex) are usually used ...