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Clostridium botulinumneurotoxin A induces apoptosis and mitochondrial oxidative stress via activation of TRPM2 channel signaling pathway in neuroblastoma and glioblastoma tumor cells
Akpınar, Orhan; Özşimşek, Ahmet; Güzel, Mustafa; Nazıroğlu, Mustafa (Taylor & Francis Ltd, 2020)Background TheClostridium botulinumneurotoxin A (BTX) is a polypeptide produced by the bacteriumClostridium botulinum. In addition to the therapeutic actions of BTX against pain and neuromuscular disorders, it is acted as ... -
Clot retention: Our experiences with a simple new technique of evacuation with a thoracic catheter
Aydın, Cemil; Şenturk, Aykut Buğra; Akkoç, Ali; Topaktaş, Ramazan; Aydın, Zeynep B.; Ekici, Musa (Cureus Inc, 2019)Introduction: Clot retention in the urinary bladder is a very common health problem in surgical and nonsurgical cases and clot retention treatment is quite costly. Objectives: The aim of this retrospective study was to ... -
Coffee induces AHR- and Nrf2-mediated transcription in intestinal epithelial cells
Toydemir, Gamze; Loonen, Linda M. P.; Venkatasubramanian, Prashanna Balaji; Mes, Jurriaan J.; Wells, Jerry M.; De Wit, Nicole (Elsevier Sci Ltd, 2021)Coffee induces a health-promoting adaptive response of cells in the body. Here, we investigated enterocyte responses to AHR agonists in coffee and measured their transport across a polarized intestinal epithelium. ... -
The colostrum quality and composition of simmental and brown swiss heifers
Yaylak, Erdal; Güley, Ziba; Sayan, Yılmaz; Kulay, Taner (Univ Federal Uberlandia, 2018)The present study was conducted to determine the quality and composition of colostrum samples obtained from Simmental and Brown Swiss heifers on a Turkish dairy farm in Odemis, Izmir. The average volume of colostrum obtained ... -
A comparative assessment of bagging ensemble models for modeling concrete slump flow
Aydoğmuş, Hacer Yumurtacı; Erdal, Halil İbrahim; Karakurt, Onur; Namlı, Ersin; Türkan, Yusuf S.; Erdal, Hamit (Techno-Press, 2015)In the last decade, several modeling approaches have been proposed and applied to estimate the high-performance concrete (HPC) slump flow. While HPC is a highly complex material, modeling its behavior is a very difficult ... -
Comparison of bioactive components, antimicrobial and antimutagenic features of organically and conventionally grown almond hulls
Murathan, Zehra Tuğba; Kaya, Armağan; Erbil, Nurcan; Arslan, Mehmet; Diraz, Emel; Karaman, Şengül (Springer, 2020)In Turkey, almonds are grown via the following three methods: organic (O), conventional (C) and good agricultural practice (GAP). Almond seeds are mostly consumed as nuts; thus, the researchers have focused different ... -
Comparison of laparoscopic and open appendectomy on wound infection and healing in complicated appendicitis
Güler, Yılmaz; Karabulut, Zülfikar; Çalış, Hasan; Şengül, Serkan (Wiley, 2020)The aim of this study was to investigate the effects of laparoscopic and open surgery on the development of postoperative surgical wound infection and wound healing between complicated appendicitis patients. Patients with ... -
Comparison of root resorption after bone-borne and tooth-borne rapid maxillary expansion evaluated with the use of microtomography
Yıldırım, Mücahid; Akın, Mehmet (Mosby-Elsevier, 2019)Introduction: Root resorption was compared between bone-borne and tooth tissue-borne rapid maxillary expansion patients with the use of microtomography. Methods The study included 20 patients (ages 11-16 years) requiring ... -
Comparison of single event multilevel surgery and multiple surgical events in the lower extremities of children with spastic cerebral palsy
Objectives: This study aims to compare patients treated with single event multilevel surgery (SEMS) and multiple surgical events (MSE) for disorders of the lower extremities due to cerebral palsy (CP). Patients and methods: ... -
Computation of k-ary Lyndon words using generating functions and their differential equations
Küçükoğlu, İrem; Şimşek, Yılmaz (Univ Nis, Fac Sci Math, 2018)By using generating functions technique, we investigate some properties of the k-ary Lyndon words. We give an explicit formula for the generating functions including not only combinatorial sums, but also hypergeometric ... -
Continuous erythropoietin receptor activator ameliorates diabetic kidney disease in rats
Günal, Mehmet Yalçın; Eren, Zehra; Bakır, Elif Arı (Aves, 2020)Objective: Diabetic kidney disease (DKD) is still a significant cause of morbidity in patients with diabetes. In this study, we examined the potential effects of continuous erythropoietin receptor activator (CERA) on ... -
Copy number variation and regions of homozygosity analysis in patients with MULLERIAN aplasia
Ekşi, Durkadın Demir; Shen, Yiping; Erman, Münire; Chorich, Lynn P.; Sullivan, Megan E.; Bilekdemir, Meriç; Layman, Lawrence C. (Biomed Central Ltd, 2018)Background: Little is known about the genetic contribution to Mullerian aplasia, better known to patients as Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome. Mutations in two genes (WNT4 and HNF1B) account for a small number ... -
The crisis of folkloric heritage and its social effects from organic doctrine to postmodern digital policy
Öztürk, Ali; Emre, İsmet (Geleneksel Yayincilik Ltd Stl, 2020)In the modern era, all forms of production that build a society have undergone many oriented-intended or necessary changes. Although folklore is a modern definition, its ontology, function and role are as old as human ... -
Cytokine expression profiles in autism spectrum disorder: A multi-center study from Turkey
Kütük, Meryem Özlem; Tufan, Evren; Gökçen, Cem; Kılıçaslan, Fethiye; Karadağ, Mehmet; Mutluer, Tuba; Kütük, Özgür (Academic Press Ltd- Elsevier Science Ltd, 2020)Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder characterized by impairments in communication and social interaction as well as restricted interests and repetitive behaviors. The pathogenesis of ASD ... -
Çalışan ve çalışmayan ergenlerin zorbalık davranışının çeşitli değişkenler açısından incelenmesi
Atav, Pelin Ülker; Baran, Gülen (2020)Çalışmak; çocukların ve ergenlerin fiziksel, zihinsel, sosyal-duygusal gelişimlerinin yolunda gitmesine engel olabilmektedir. Çalışan ergenler düşük benlik algısına sahip olabilmekte, okula devam edememenin yanı sıra, okula ... -
Detection of architectural drawings errors in 3 dimension
Kazaz, Aynur; Acıkara, Turgut; Ulubeyli, Serdar; Koyun, Hasan (Elsevier Science Bv, 2017)In construction projects architectural drawings are the main documents which show how a structure has to be built. In this sense, most of the data necessary for project management are prepared based on these drawings. ... -
Determination and classification of cutaneous innervation of the dorsum of the foot in foetal cadavers
Candan, Büşra; Albay, Soner (Via Medica, 2018)Background: The aim of this study is to determine cutaneous innervation of the dorsum of the foot on foetal cadavers. Materials and methods: In this study. 200 limbs from 100 embalmed foetuses (54 males and 46 females) ... -
Determination and classification of intraoral phosphor storage plate artifacts and errors
Deniz, Yeşim; Kaya, Seher (Korean Acad Oral & Maxillofacial Radiology, 2019)Purpose: The aim of this study was to determine the reasons and solutions for intraoral phosphor storage plate (PSP) image artifacts and errors, and to develop an appropriate classification of the artifacts. Materials and ... -
Determination of attributes affecting price-performance using fuzzy rule-based systems: online ratings of hotels by travel 2.0 users
Doğan, Seden; Başaran, Murat Alper; Kantarcı, Kemal (Emerald Group Publishing Ltd, 2020)Purpose Fuzzy rule-based system (FRBS), a soft computing method used for big data analysis, is used to determine which single hotel attribute or interrelated hotel attributes used in Travel 2.0 data play a role on ...