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dc.contributor.authorAksoy, Fatih
dc.contributor.authorAydın, Baş, Hasan
dc.contributor.authorBağcı, Ali
dc.contributor.authorBasri Savaş, Hasan
dc.date.accessioned2021-02-19T21:20:44Z
dc.date.available2021-02-19T21:20:44Z
dc.date.issued2021
dc.identifier.issn0870-2551
dc.identifier.urihttps://doi.org/10.1016/j.repc.2020.08.010
dc.identifier.urihttps://hdl.handle.net/20.500.12868/639
dc.description.abstractBackground: Contrast-induced nephropathy (CIN) is a life-threatening complication after primary percutaneous coronary intervention (p-PCI). Oxidative stress and inflammation may play an important role in the development of CIN. Objective: We aimed to assess the relationship between total oxidant status, total antioxidant capacity, high-sensitivity C-reactive protein (hs-CRP), gamma-glutamyltransferase and uric acid (UA) in the development of CIN in patients presenting with ST-elevation myocardial infarction (STEMI). Methods: This prospective cohort study consisted of 341 patients with STEMI. Patients were divided into two groups: those with and those without CIN. Predictors of CIN were determined by multivariate regression analyses. Results: Multivariate regression analysis showed that initial glucose level, contrast media volume/glomerular filtration ratio (eGFR) ratio, hs-CRP, UA and oxidative status index were associated with the development of CIN in patients with STEMI. Conclusion: The main finding of this study is that increased oxidative stress and inflammation parameters were associated with the development of CIN in patients with STEMI. Other independent predictors of CIN were contrast media volume/eGFR ratio, initial glucose level, UA and hs-CRP. © 2020 Sociedade Portuguesa de Cardiologiaen_US
dc.language.isoengen_US
dc.publisherSociedade Portuguesa de Cardiologiaen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectContrast-induced nephropathyen_US
dc.subjectOxidant and antioxidant statusen_US
dc.subjectST-segment elevation myocardial infarctionen_US
dc.titlePredictive value of oxidant and antioxidant status for contrast-induced nephropathy after percutaneous coronary intervention for ST-segment elevation myocardial infarctionen_US
dc.title.alternativeValor preditivo dos estados oxidante e antioxidante na nefropatia de contraste após intervenção coronária percutânea em enfarte do miocárdio com elevação do segmento STen_US
dc.typearticleen_US
dc.contributor.departmentALKÜen_US
dc.contributor.institutionauthor0-belirlenecek
dc.identifier.doi10.1016/j.repc.2020.08.010
dc.relation.journalRevista Portuguesa de Cardiologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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