Ara
Toplam kayıt 6, listelenen: 1-6
Protective effects of N-acetyl cysteine against paclitaxel-induced cardiotoxicity through modulation of transient receptor potential melastatin 2 channels
(Gazi Univ, Fac Med, 2019)
Aim : In our study, we investigated the paclitaxel induced cardiotoxicity and alterations in Ca2+ influx, oxidative stress and apoptosis through transient receptor potential melastatin 2 (TRPM2) channels and modulator role ...
Apoptotic efficiency of capecitabine and 5-fluorouracil on human cancer cells through TRPV1 channels
(Natl Inst Science Communication-Niscair, 2020)
The expression of transient receptor potential protein channels increases intensively colon and breast cancer cells. We aimed to reveal the role of 5-fluorouracil (5FU) and capecitabine along with Transient Receptor Potential ...
Comprehensive research on past and future therapeutic Strategies devoted to treatment of amyotrophic lateral sclerosis
(2022)
Amyotrophic lateral sclerosis (ALS) is a rapidly debilitating fatal neurodegenerative disorder, causing muscle atrophy and weakness, which leads to paralysis and eventual death. ALS has a multifaceted nature affected by ...
Melanoma hücrelerinde epoksomisinin indüklediği apoptozis sürecinde gerçekleşen erken spektral değişikliklerin belirlenmesi
(2021)
Amaç: Hücrelerde apoptozis sürecinde meydana gelen spektral değişikliklerin belirlenmesi yeni tedavi ve ilaç araştırmalarına önemli bilgiler sağlayabilir. Apoptotik hücreler, hücre küçülmesi ve parçalanmasına yol açan bir ...
Real-Time Detection of Doxorubicin-InducedApoptosis in Breast Cancer Cells Using the BackReflection Spectroscopy
(2021)
Apoptosis detection methods cause the cell culture medium to be physically or chemically affected. In addition, these methods have disadvantages such as cost and cell losses. The aim of this study is to develop a method ...
Alzheimer Hastalığının Önlenmesi ve Tedavisinde Melatoninin TRPA1 Kanalları Üzerinden Potansiyel Etkileri
(2022)
Amaç: Alzheimer hastalığı (AH) demansın en yaygın nedenidir ve ilerleyici bir nörodejeneratif hastalık olarak tanımlanır. AH ilerleyici bozukluğunun ana klinik özellikleri öğrenme ve hafıza kaybıdır. Çeşitli çalışmalar ...