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Agomelatine could prevent brain and cerebellum injury against LPS-induced neuroinflammation in rats
(Academic Press Ltd- Elsevier Science Ltd, 2020)
Sepsis, systemic hyper-inflammatory immune response, causes the increase of morbidity and mortality rates due to multi-organ diseases such as neurotoxicity. Lipopolysaccharide (LPS) induces inflammation, oxidative stress ...
Melatonin protects the heart and endothelium against high fructose corn syrup consumption-induced cardiovascular toxicity via SIRT-1 signaling
(Sage Publications Ltd, 2019)
High fructose corn syrup (HFCS) has been shown to cause cardiovascular toxicity via oxidative stress and inflammation. The aim of this study is to demonstrate the protective effects of melatonin (MLT) against HFCS-induced ...
Sıçanlarda indometazin ile indüklenmiş peptik ülser modelinde tarantula cubensis ekstraktının gastroprotektif etkisi
(Alanya Alaaddin Keykubat Üniversitesi, 2020)
Amaç: Gastrik ülser, endüstrileşmiş dünyada çeşitli faktörler nedeniyle en sık görülen gastrointestinal hastalıktır. Bununla birlikte mide ülseri, gastrointestinal sağlığın korunması için genellikle tercih edilen proton ...