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Toplam kayıt 921, listelenen: 91-100
Clostridium botulinumneurotoxin A induces apoptosis and mitochondrial oxidative stress via activation of TRPM2 channel signaling pathway in neuroblastoma and glioblastoma tumor cells
(Taylor & Francis Ltd, 2020)
Background TheClostridium botulinumneurotoxin A (BTX) is a polypeptide produced by the bacteriumClostridium botulinum. In addition to the therapeutic actions of BTX against pain and neuromuscular disorders, it is acted as ...
Identification of radical structures on 1-pentamethylbenzyl-3-ethylimidazoliumsilver(I)bromide and 1,3-bis(pentamethylbenzyl)-4,5-dimethylbenzimidazoliumsilver(I)bromide exposed to gamma rays: an EPR study
(Wiley, 2016)
1-Pentamethylbenzyl-3-ethylimidazoliumsilver(I)bromide and 1,3-bis(pentamethylbenzyl)-4,5dimethylbenzimidazoliumsilver(I)bromide and their Ag+ complexes were synthesized and their polycrystal forms were produced by ...
Minocycline increases in-vitro cortical neuronal cell survival after laser induced axotomy
(Bentham Science Publ Ltd, 2020)
Background: Antibiotic therapies targeting multiple regenerative mechanisms have the potential for neuroprotective effects, but the diversity of experimental strategies and analyses of non-standardised therapeutic trials ...
Synergic and comparative effect of 5-fluorouracil and leucoverin on breast and colon cancer cells through TRPM2 channels
(Comenius Univ, 2018)
OBJECTIVES: We aimed to reveal the role of 5-fluorouracil (5-FU) and Leucovorin (LV) along with transient receptor potential protein melastatin 2 (TRPM2) channels in breast and colon cancer cells during the treatment ...
Selenium enhances TRPA1 channel-mediated activity of temozolomide in SH-SY5Y neuroblastoma cells
(Springer, 2020)
Purpose Neuroblastoma is a malignant solid tumor that originates from the sympathetic nervous system in early childhood. Temozolomide is used for treatment in high-risk groups with low treatment response of neuroblastomas. ...
The effect of intracerebral structure volumes on idiopathic intracranial hypertension
(Lippincott Williams & Wilkins, 2021)
Background This aim of this study was to assess the effect of idiopathic intracranial hypertension (IIH) in the development of intracranial hypertension by measuring patients' cerebrospinal fluid (CSF), brain, and segment ...
The relationship between ureteral obstruction time and secondary signs in computed tomography due to ureteral stone obstruction
(Coll Physicians & Surgeons Pakistan, 2020)
Objective: To investigate the relationship between numerical values obtained using computed tomography (CT) in stone-related urinary obstruction and the duration of obstruction. Study Design: Cross-sectional study. Place ...
A rare case of salmonellosis with multifocal osteomyelitis and pulmonary involvement
(Elsevier Science London, 2020)
Salmonellosis is characterized by gastroenteritis and enteric fever in humans and affects various organs, particularly in endemic regions and in immunocompromised patients. Here, we report on a 45-year-old male patient ...
The effect of melatonin on digoxin-induced cardiac damage in cardiomyocytes
(Comenius Univ, 2019)
OBJECTIVES: Digoxin is a cardiac glycoside which is widely used in cardiovascular medicine. Oxidative stress, as well as intracellular Ca2+ overload, plays an important role in digoxin toxicity. Transient receptor potential ...
The role of selenium in bevacizumab induced cardiotoxicity
(Comenius Univ, 2019)
OBJECTIVE: We investigated the role of selenium in bevacizumab induced cardiotoxicity and involvement of transient receptor potential vanilloid 1 (TRPV1) channels in cardiomyocytes. MATERIALS AND METHODS: All cells (Human ...