Yazar "ALKÜ, Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü" için Araştırma Çıktıları (TR Dizin / Web of Science / Scopus / PubMed) listeleme
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Alzheimer Hastalığının Önlenmesi ve Tedavisinde Melatoninin TRPA1 Kanalları Üzerinden Potansiyel Etkileri
Özşimşek, Ahmet; Övey, İshak Suat (2022)Amaç: Alzheimer hastalığı (AH) demansın en yaygın nedenidir ve ilerleyici bir nörodejeneratif hastalık olarak tanımlanır. AH ilerleyici bozukluğunun ana klinik özellikleri öğrenme ve hafıza kaybıdır. Çeşitli çalışmalar ... -
Analysis of mitochondrial DNA cytochrome-b (CYB) and ATPase-6 gene mutations in COVID-19 patients
Coronavirus disease of 2019 (COVID‐19) is a pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Mutations of mitochondrial DNA (mtDNA) are becoming increasingly common in various diseases. ... -
Association between vitamin D levels and frequency of disease exacerbations and hospitalizations in patients with COPD
Introduction: Chronic obstructive pulmonary disease (COPD) is a debilitating disorder that restricts the physical activity of patients who are deprived of sunlight, which is a source of vitamin D. The purpose of this study ... -
The association of non-motor symptoms with motorsymptoms in parkinson’s disease
Çankaya, Şeyda (2021)Aim: Idiopathic Parkinson’s disease (IPD) is the second most common progressive neurodegenerative disorder and well known with typical motor impairment. Besides motor symptoms, non-motor symptoms (NMS) occur very frequently ... -
Bilateral Alt Ekstremite Ameli: Olgu Sunumu
Ameli bir ekstremitenin tamamen olmaması anlamına gelir. Bu anomali izole olabileceği gibi multipl konjenital anomalilerin bir parçası olarak da bulunabilir. Ender görülen ve genellikle etyolojisi saptanamayan bir durumdur. ... -
Broadly effective metabolic and immune recovery with C5 inhibition in CHAPLE disease
Özen, Ahmet; Kasap, Nurhan; Vujkovic-Cvijin, Ivan; Apps, Richard; Cheung, Foo; Karakoç Aydıner, Elif; Akkelle, Bilge; Sarı, Sinan; Tutar, Engin; Özcay, Figen; Sayar, Ersin; Lenardo, Michael J. (2021)CHAPLE disease is a lethal syndrome caused by genetic loss of the complement regulatory protein CD55. Lenardo, Ozen and their colleagues report that blockade of C5 complement activation in a small cohort of pediatric ... -
Characteristics and outcomes of acute kidney injury in hospitalized COVID-19 patients: A multicenter study by the Turkish society of nephrology
Arıkan, Hakkı; Öztürk, Savaş; Tokgöz, Bülent; Dursun, Belda; Seyahi, Nurhan; Trabulus, Sinan; İslam, Mahmud; Ayar, Yavuz; Görgülü, Numan; Karadağ, Serhat; Eren,Zehra; Tuğlular, Serhan (2021)Background Acute kidney injury (AKI) is common in coronavirus disease-2019 (COVID-19) and the severity of AKI is linked to adverse outcomes. In this study, we investigated the factors associated with in-hospital outcomes ... -
Clinical and radiological characteristics of pulmonary actinomycosis mimicking lung malignancy
Pulmonary actinomycosis, clinically and radiologically, mimics abscess, tuberculosis, and lung malignancy, resulting in misdiagnosis or delay in diagnosis. In this study, we analyzed the clinicoradiological features of ... -
Clinical and radiological characteristics of pulmonary actinomycosis mimicking lung malignancy
INTRODUCTION: Pulmonary actinomycosis, clinically and radiologically, mimics abscess, tuberculosis, and lung malignancy, resulting in misdiagnosis or delay in diagnosis. In this study, we analyzed the clinicoradiological ... -
Clinical features, risk factors, and antimicrobial resistance of pseudomonas putida isolates
Pseudomonas putida rarely results in infection, primarily in patients undergoing invasive procedures or immunocompromised hosts. We aimed to investigate the characteristics of Pseudomonas putida infections. This is a ... -
A clue for obstructive sleep apnea hidden in tomographic images of idiopathic pulmonary fibrosis patients
Objectives: The most common opinion about apnea/hypopnea formation in restrictive pulmonary diseases is based on decreased lung volumes causing upper airway collapse. This study targets to reveal some evidence for this ... -
Combined metabolic activators improve cognitive functions in Alzheimer’s disease patients: a randomised, double-blinded, placebo-controlled phase-II trial
Yuluğ, Burak; Altay, Özlem; Li, Xiangyu; Hanoğlu, Lütfü; Çankaya, Şeyda; Lam, Simon; Velioğlu, Halil Aziz; Yang, Hong; Coşkun, Ebru; İdil, Ezgi; Nogaylar, Rahim; Özşimşek, Ahmet; Bayram, Cemil; Bolat, İsmail; Öner, Sena; Tozlu, Özlem Özdemir; Arslan, Mehmet Enes; Hacımüftüoğlu, Ahmet; Yıldırım, Serkan; Arif, Muhammad; Shoaie, Saeed; Zhang, Cheng; Nielsen, Jens; Turkez, Hasan; Boren, Jan; Uhlen, Mathias; Mardinoğlu, Adil (2023)Abstract Background Alzheimer’s disease (AD) is associated with metabolic abnormalities linked to critical elements of neurodegeneration. We recently administered combined metabolic activators (CMA) to the AD rat model ... -
A comparison of idiopathic pulmonary fibrosis and chronic hypersensitivity pneumonia in terms of anterior mediastinal fat properties
Bulut, Sertan; Çelik, Deniz; Ertürk, Hakan; Karamanlı, Harun; Şahin, Mustafa Engin; Sönmez, Özlem; Biber, Çiğdem (2022)Aim: The shape and physical properties of the anterior mediastinum can be easily affected by inflammatory lung diseases, tuberculosis, empyema, radiotherapy, chronic fibrotic lung diseases, previous surgery, and after ... -
Comprehensive research on past and future therapeutic Strategies devoted to treatment of amyotrophic lateral sclerosis
Sever, Belgin; Çiftçi, Halil İbrahim; Demirci,Hasan; Sever, Hilal; Ocak, Firdevs; Yuluğ, Burak; Tateishi, Hiroshi; Tateishi, Takahisa; Otsuka, Masami; Fujita, Mikako; Başak, Ayşe Nazlı (2022)Amyotrophic lateral sclerosis (ALS) is a rapidly debilitating fatal neurodegenerative disorder, causing muscle atrophy and weakness, which leads to paralysis and eventual death. ALS has a multifaceted nature affected by ... -
The correlations between pulmonary function tests and polysomnographic parameters in overlap syndrome
Duyar, Sezgi Şahin; Çelik, Deniz; Fırat, Selma (2022)Aim: This study aims to reveal the relationship between Pulmonary Function Tests (PFTs) parameters and polysomnographic parameters. It aims to determine the guiding values in treatment selection, with the hypothesis that ... -
Crimean-Congo Hemorrhagic Fever (CCHF) and Brucellosis Coinfection in Antalya: A Case Report
Erdoğan, Aşkın; Erdoğan, Haluk (2023)The combination of Crimean-Congo hemorrhagic fever (CCHF) and brucellosis is unusual and can easily go unnoticed. Herein we report a case of CCHF and brucellosis coinfection and review the pertinent literature. The presented ... -
Different clinical courses with the same findings: two cases of paroxysmal nocturnal hemoglobinuria presenting with thrombocytopenia
Karakuş, Volkan; Kaya, Egemen; Dere, Yelda; Şahin, Fahri (2021)Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal stem cell disease that manifests with chronic intravascular hemolysis, thrombosis, and bone marrow failure. Various degrees of cytopenias accompany the disease. Although ... -
Differentiation of claustrum resting-state functional connectivity in healthy aging, Alzheimer's disease, and Parkinson's disease
Ayyıldız, Sevilay; Velioğlu, Halil Aziz; Ayyıldız, Behçet; Sütçübaşı, Bernis; Hanoğlu, Lütfü; Bayraktaroğlu, Zübeyir; Yıldırım, Süleyman; Atasever, Alper; Yuluğ, Burak (2023)The claustrum is a sheet-like of telencephalic gray matter structure whose function is poorly understood. The claustrum is considered a multimodal computing network due to its reciprocal connections with almost all cortical ... -
The differentiation of metastatic mediastinal lymph nodes From benign hypermetabolic lesions
Bulut, Sertan; Çelik, Deniz; Karamanlı, Harun; Aktaş, Zafer; Özmen, Özlem; Ertürk, Hakan; Gürçay, Nesrin; Biber, Çiğdem (2022)Background Anthracosis may cause a positron emission tomography/computed tomography (PET/CT) false positivity in mediastinal and hilar lymph nodes. We aimed to evaluate the radiological features and the maximum standardized ... -
The Effect of COVID-19 on Radiation Oncology Practice in Türkiye
Tuğrul, Fuzuli; Beypınar, İsmail; Sayık, Dilek (2022)OBJECTIVE COVID-19 (Coronavirus Disease-19) was the name given to a novel pneumonia outbreak that occurred in Wuhan (Hubei province, China) in December 2019. For patients undergoing or scheduled for radiation therapy, ...