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Evaluation of the bilateral cardiac afferent distribution at the spinal and vagal ganglia by retrograde labeling 

Çağlar, Tuba Akgül; Durdu, Zeynep Begüm; Turhan, Mehmet Uğurcan; Günal, Mehmet Yalçın; Aydın, M. S.; Özturk, Gürkan; Çağavi, Esra (Elsevier, 2021)
The identity of sensory neurons innervating the heart tissue and the extent of information reported to the brain via these neurons are poorly understood. In order to evaluate the multidimensional distribution and abundance ...

An alternative approach wound healing field with Polypodium vulgare 

Batur, Şebnem; Ayla, Şule; Şakul, Ayşe Arzu; Okur, Mehmet Evren; Karadağ, Ayşe Esra; Daylan, Benay; Günal, Mehmet Yalçın (Logos Medical Publishing, 2020)
Objective: In this study, we examined the effects of Polypodium vulgare L. (Polypodiaceae) as a candidate to be used for wound healing scarred area. We investigated the antibacterial, and antioxidant activity of P. Vulgare ...

A different view on the platelet aggregation inhibitor clopidogrel - a well-suitable anti-oedema agent in a preclinical model of brain injury? 

Günal, Mehmet Yalçın; Yuluğ, Burak; Çağlayan, Berrak; Ozansoy, Mehmet; Kılıç, Ülkan; Keskin, İlknur; Kılıç, Ertuğrul (Czech Medical Soc, 2019)
Aim: The neuroprotective effects of clopidogrel have already been shown in various experimental models. Taking into account the fact that clopidogrel is well tolerated and approved for use in various clinical settings, it ...

The effects of carvacrol on oxidative stress parameters and adoptosis process via TRPA1 channels in neuroblastoma cells 

Günal, Mehmet Yalçın; Övey, İshak Suat (Polskie Towarzystwo Farmaceutyczne, 2019)
Objectives: This study is a preliminary study to investigate the effects of carvacrol (CRV) obtained from thyme on the apoptosis process in neuroblastoma cells. Methods: In this study, seven groups were designed as control, ...

Wound healing effects of methanol extract of Laurocerasus officinalis roem 

Ayla, Şule; Okur, Mehmet Evren; Günal, Mehmet Yalçın; Özdemir, Ekrem Musa; Polat, Derya Çiçek; Yoltaş, Ayşegül; Biçeroğlu, Özge; Karahüseyinoğlu, Serçin (Taylor & Francis Ltd, 2019)
Laurocerasus officinalis Roem. (syn: Prunus laurocerasus L.) is a member of Rosaceae family. We investigated the antimicrobial and antioxidant activity of L. officinalis Roem in wound healing both in vivo and in vitro using ...

Continuous erythropoietin receptor activator ameliorates diabetic kidney disease in rats 

Günal, Mehmet Yalçın; Eren, Zehra; Bakır, Elif Arı (Aves, 2020)
Objective: Diabetic kidney disease (DKD) is still a significant cause of morbidity in patients with diabetes. In this study, we examined the potential effects of continuous erythropoietin receptor activator (CERA) on ...

Prunus spinosa L. meyvelerinin deneysel yara iyileşmesi üzerine etkileri 

Ayla, Şule; Günal, Mehmet Yalçın; Şakul, Ayşe Arzu Sayın; Biçeroğlu, Özge; Özdemir, Ekrem Musa; Okur, Mehmet Evren; Bilgiç, Bülent Emre (2017)
Farelerde oluşturduğumuz deneysel yara modellerinde, Prunus Spinosa L. metanollü meyve ekstresini kullanarak, bu ekstrenin yara iyileşmesindeki etkisini araştırdık. Otuz iki adet C57/Black fare ile 4 deney grubu oluşturuldu. ...

The effects of topical liposomal resveratrol on incisional and excisional wound healing process 

Günal, Mehmet Yalçın; Ayla, Şule; Bedri, Nejda; Beker, Mustafa Çağlar; Çağlayan, Ahmet Burak; Aslan, İsmail; Kılıç, Ülkan (2019)
Background and Design: The objective of this study was to investigate the wound healing activity of different concentrations of liposomal trans-resveratrol formulations on incisional and excisional wounds in rats. Materials ...

The effect of rifampicin on the neuronal cell survival in primary cortical neuron culture after laser axotomy 

Ozansoy, Mehmet; Coşkun, Ebru; Ozansoy, Muzaffer Beyza; Çankaya, Şeyda; Günal, Mehmet Yalçın; Bayraktaroğlu, Zübeyir; Hanoğlu, Lütfü (Alanya Alaaddin Keykubat Üniversitesi, 2019)
Aim: Neurodegeneration caused by the axonal injury is a widely seen phenomenon in spinal cord and traumatic brain injuries. Due to the disintegration of the synaptic connection neurotrophic factors could not be transported ...

Squalene attenuates the oxidative stress and activates AKT/mTOR pathway against cisplatin-induced kidney damage in mice 

Sakul, Arzu; Ozansoy, Mehmet; Elibol, Birsen; Ayla, Şule; Günal, Mehmet Yalçın; Yozgat, Yasemin; Kılıç, Ülkan (2019)
The clinical use of cisplatin, which is a first-line anticancer agent, is highly restricted due to its adverse effects on kidneys that lead to nephrotoxicity. Therefore, some potential reno-protective substances have been ...
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