Browsing by Author "Savaş, Hasan Basri"
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Ameliorative effects of pregabalin on LPS induced endothelial and cardiac toxicity
Aşçı, Halil; Özmen, Özlem; Erzurumlu, Yalçın; Savaş, Hasan Basri; Temel, Esra Nurlu; İçten, Pelin; Hasseyid, N. (Taylor & Francis Ltd, 2020)We investigated the antioxidant, anti-inflammatory and anti-apoptotic effects of pregabalin (PREG) on lipopolysaccharide (LPS) induced sepsis related cardiotoxicity via NF-k beta pathways. We used 24 female Wistar albino ... -
Bir geleneksel ve tamamlayıcı tıp uygulama merkezinde yaş kupa terapisi ve Hirudoterapi yapılan hastaların laboratuvar sonuçlarının ve tansiyon ölçümlerindeki değişimin incelenmesi
Sarıkan, İsmail; Savaş, Hasan Basri (2020)Amaç: Geleneksel ve tamamlayıcı tıp (GETAT) uygulamaları, dünya genelinde yaygın olarak yapılmaktadır. Bu çalışmada, ALKÜ Alanya Eğitim ve Araştırma Hastanesi Geleneksel ve Tamamlayıcı Tıp (GETAT) Uygulama Merkezine 30 ... -
Bir Tıp Fakültesi Son Sınıf Öğrencilerinin Sağlıklı Beslenme ve Helal Gıdaya İlişkin Bilgi ve Tutumları
Yürekli, Mustafa Volkan; Başaran, Özgür; Savaş, Hasan Basri; Kişioğlu, Ahmet Nesimi (Alanya Alaaddin Keykubat Üniversitesi, 2017)Amaç: Bu çalışmada, tıp fakültesi son sınıf öğrencilerinin helal ve sağlıklıgıda ile alakalı bilgi, tutum, davranış ve algılarının ölçülmesi amaçlandı.Yöntemler: Süleyman Demirel Üniversitesi Tıp Fakültesi sonsınıfında ... -
Calorie restriction protects against apoptosis, mitochondrial oxidative stress and increased calcium signaling through inhibition of TRPV1 channel in the hippocampus and dorsal root ganglion of rats
Gültekin, Fatih; Nazıroğlu, Mustafa; Savaş, Hasan Basri; Çiğ, Bilal (Springer/Plenum Publishers, 2018)The TRPV1 channel is activated in neurons by capsaicin, oxidative stress, acidic pH and heat factors, and these factors are attenuated by the antioxidant role of calorie restriction (CR). Hence, we investigated the hypothesis ... -
Cilostazol induces angiogenesis and regulates oxidative stress in adose-dependent manner: A chorioallantoic membrane study
Background: In this study, we aimed to investigate the effects ofcilostazol on angiogenesis and oxidative stress using the chorioallantoicmembrane model. Methods: In this experimental study, the Ross 308 chick embryos ... -
Circulation levels of acute phase proteins pentraxin 3 and serum amyloid a in atherosclerosis have correlations with periodontal inflamed surface area
Temelli, Başak; Yetkin Ay, Zuhal; Savaş, Hasan Basri; Aksoy, Fatih; Kumbul Doğuç, Duygu; Uskun, Ersin; Varol, Ercan (Univ Sao Paulo Fac Odontologia Bauru, 2018)Objectives: One of the plausible mechanisms in the relationship between periodontitis and coronary artery disease (CAD) is the systemic inflammatory burden comprised of circulating cytokines/mediators related to periodontitis. ... -
Effects of nutrition style on neuro-behavior
Savaş, Hasan Basri; Gültekin, Fatih; Doğuç, Duygu Kumbul (Allied Acad, 2017)Objective: The effects of meal frequency and caloric restriction on spatial memory based on hippocampus in rats were examined in our study. Materials and methods: As a result of a four-weeks pilot study amount of food and ... -
Enzymatic behavior of laccase following interaction with gamma-CD and immobilization into PCL nanofibers
Canbolat, Mehmet Fatih; Savaş, Hasan Basri; Gültekin, Fatih (Academic Press Inc Elsevier Science, 2017)This study examines the effects of CD use on enzymatic activity, following enzyme immobilization into nanofibers. There is almost no research available on the change in enzyme activity following interaction with cyclodextrin ... -
Food additives and microbiota
The use of food additives in food production is inevitable in this modern world. Although only a safe amount of food additives is approved, their safety has always been questioned. To our knowledge, the effects of food ... -
Gebelerde ikinci trimester tarama testinde biyokimyasal belirteçler ile gebelik komplikasyonları arasındaki ilişki
Savaş, Hasan Basri; Köse, Seyit Ali; Güler, Mesut; Gültekin, Fatih (Alanya Alaaddin Keykubat Üniversitesi, 2017)Amaç: Downsendromu, neural tube defects (NTDs), vetrizomi 18 riskinin ve ayrıca AFP,uE3 ve beta hCGseviyelerinin her biri ile doğum öncesi maternal veya fetal komplikasyonlarınve doğum sonrası kromozomal anomalilerin, ... -
Genetiği değiştirilmiş gıdalar ve insan sağlığına etkileri
Çatalbaş, Tahir; Savaş, Hasan Basri; Gültekin, Fatih (Alanya Alaaddin Keykubat Üniversitesi, 2017)Organizmalarıngenetik yapısının değiştirildiği genetik mühendisliği konusu, bilimselplatformlarda hâlâ tartışılmaktadır. Genetiği değiştirilmiş organizmalarıdestekleyen gruplar, bu teknolojinin besin kalitesinin ve sağlığa ... -
Helal gıda belgelendirmesinde biyokimya laboratuvarının rolü
Savaş, Hasan Basri; Çatalbaş, Tahir; Gültekin, Fatih (Alanya Alaaddin Keykubat Üniversitesi, 2017)ÖZET “Helal” sözcüğü Türk Dili’nde: “Dinikurallara aykırı olmayan” olarak tanımlanır. “Helal Gıda” kavramı, “İslâmîkurallar doğrultusunda izin verilen gıda” anlamında kullanılmaktadır. Helalgıda sertifikaları; sertifika ... -
Improved catalytic activity by catalase immobilization using -cyclodextrin and electrospun PCL nanofibers
Canbolat, M. Fatih; Savaş, Hasan Basri; Gültekin, Fatih (Wiley, 2017)Nanofibrous structures are promising for biocatalyst immobilization due to their large surface area which facilitates the enzyme attachment, stability, ease of separation, and fine porous structure. There is limited research ... -
İnsülin direnci ve klinik önemi
Gültekin, Fatih; Savaş, Hasan Basri (2017)İnsülin metabolizmanın düzenleyici temel hormonlarından biridir. İnsülinin keşfi için uzun asırlar boyu süren araştırmalar mevcuttur. Bilim adamlarını insülini araştırmaya iten sebep insülin direncinin ortaya çıkardığı ... -
A Mathematical modelling approach in the spread of the novel 2019 Coronavirus SARS-CoV-2 (COVID-19) pandemic
Çakır, Zafer; Savaş, Hasan Basri (Modestum Ltd, 2020)The novel 2019 coronavirus, SARS-CoV-2 (COVID-19), emerged towards the end of 2019 in the city of Wuhan in the province of Hubei in the People's Republic of China, and it has spread to the entire world very fast and in a ... -
Melatonin protects the heart and endothelium against high fructose corn syrup consumption-induced cardiovascular toxicity via SIRT-1 signaling
Savran, Mehtap; Aşçı, Halil; Özmen, Özlem; Erzurumlu, Yalçın; Savaş, Hasan Basri; Sönmez, Yasin; Şahin, Yasemin (Sage Publications Ltd, 2019)High fructose corn syrup (HFCS) has been shown to cause cardiovascular toxicity via oxidative stress and inflammation. The aim of this study is to demonstrate the protective effects of melatonin (MLT) against HFCS-induced ... -
Occupational Health Assessment of Permanent University Employees in Terms of Clinical Biochemical Data
Savaş, Hasan Basri (2021)Aim: Occupational health and safety involves important measures, trainings, and health screenings as defined by law. The existing literature on occupational medicine practices and related clinical laboratory data has ... -
Oxidant-Antioxidant Balance and Trace Elements in Children with Functional Dyspepsia
Savaş, Hasan Basri; Sayar, Ersin (2021)Objective: Functional dyspepsia (FD) is the most common functional abdominal pain disorder among children and adolescents according to the Rome IV criteria. The aim of the study was to determine the possible effect of the ... -
Parao[onase 1 Activities in First Trimester Miscarriages
Savaş, Hasan Basri; Erdem, Dilek (2021)Aim: Miscarriages are becoming increasingly important problem nowadays. First trimester pregnancy loss frequency in women of reproductive age is increasing. In this study, it is aimed to show the possible relationship ... -
Paraoxonase 1 activity as a new biochemical marker in the diagnosis of peripheral arterial disease
Savaş, Hasan Basri; Etli, Mustafa (2021)Aim: Peripheral artery disease (PAD) is an atherosclerotic disease. It is seen in older ages. It causes cardiovascular morbidity and mortality. PAD may progress without any symptoms. Despite its high frequency, there is ...