Browsing by Author "Samur, Dilara Nemutlu"
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The effects of metamizole on hematopoietic progenitor cells: Suppression of hematopoiesis stimulation in vitro
BACKGRAUND: There is evidence that the adverse effects of metamizole occur due to the effect of the drug on the hematopoietic stem/progenitor cells, and therefore, the disruption of hematopoiesis. Therefore, our study aimed ... -
Low level laser application reduces the effect of 5 fluorouracil/leucovorin combination on human breast cancer cells
Aim : 5-fluorouracil has been widely used in breast cancer treatment. Low level laser therapy (LLLT) has been shown to modulate biological processes and used in cancer treatment. It has been reported that apoptosis is ... -
The possible mechanisms of protocatechuic acid-induced central analgesia
Arslan, Rana; Aydın, Şule; Samur, Dilara Nemutlu; Bektaş, Nurcan (Elsevier Science Bv, 2018)It is aimed to investigate the central antinociceptive effect of protocatechuic acid and the involvement of stimulation of opioidergic, serotonin 5-HT2A/2C. alpha 2-adrenergic and muscarinic receptors in protocatechuic ... -
Valnoctamide: The effect on relieving of neuropathic pain and possible mechanisms
Samur, Dilara Nemutlu; Arslan, Rana; Aydın, Şule; Bektaş, Nurcan (Elsevier Science Bv, 2018)The purpose of this study is to assess the possible anti-allodynic and antihyperalgesic effect of valnoctamide, an amide derivative of valproic acid, at the doses of 40, 70 and 100 mg/kg (i.p.) in neuropathic pain model ...