Yazar "Günal, Mehmet Yalçın" için listeleme
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An alternative approach wound healing field with Polypodium vulgare
Batur, Şebnem; Ayla, Şule; Şakul, Ayşe Arzu; Okur, Mehmet Evren; Karadağ, Ayşe Esra; Daylan, Benay; Günal, Mehmet Yalçın (Logos Medical Publishing, 2020)Objective: In this study, we examined the effects of Polypodium vulgare L. (Polypodiaceae) as a candidate to be used for wound healing scarred area. We investigated the antibacterial, and antioxidant activity of P. Vulgare ... -
Can Carpobrotus edulis, heal incisional and excisional wounds on the skin?
Günal, Mehmet Yalçın; Ayla, S.; Çağlayan, B.; Beker, M.C.; Bedri, N.; Aslan, I.; Özdemir, E.M.; Kılıç, E.; Yeşilada, E. (2021)OBJECTIVES: This study aimed to investigate the wound healing activity of liposomal Carpobrotus edulis powder extract (CEPE) formulation on incisional and excisional wounds in rat. BACKGROUND: In the event of any damage, ... -
Combined therapy with probiotic VSL#3 and Omega-3 fatty acids attenuates colonic injury and inflammation in chronic DNBS-induced colitis in mice
Yoldaş İlktaç, Havvanur; Kızıltan, Gül; Lanpir, Aslı Devrim; Ozansoy, Mehmet; Günal, Mehmet Yalçın; Özmen Togay, Sine; Keskin, İlknur; Özdemir, Ekrem M.; Kılıç, Ulkan (2022)We published the abovementioned article about probiotic mixture VSL#3 on October 6, 2021. Since the product was named VSL#3 in our purchasing process in early 2016, it is referred to as VSL#3 in our article. In addition, ... -
Continuous erythropoietin receptor activator ameliorates diabetic kidney disease in rats
Günal, Mehmet Yalçın; Eren, Zehra; Bakır, Elif Arı (Aves, 2020)Objective: Diabetic kidney disease (DKD) is still a significant cause of morbidity in patients with diabetes. In this study, we examined the potential effects of continuous erythropoietin receptor activator (CERA) on ... -
A different view on the platelet aggregation inhibitor clopidogrel - a well-suitable anti-oedema agent in a preclinical model of brain injury?
Günal, Mehmet Yalçın; Yuluğ, Burak; Çağlayan, Berrak; Ozansoy, Mehmet; Kılıç, Ülkan; Keskin, İlknur; Kılıç, Ertuğrul (Czech Medical Soc, 2019)Aim: The neuroprotective effects of clopidogrel have already been shown in various experimental models. Taking into account the fact that clopidogrel is well tolerated and approved for use in various clinical settings, it ... -
The effect of probiotic and omega-3 supplements on total oxidant and total antioxidant levels in experimental colitis
İlktaç, Havvanur Yoldaş; Kızıltan, Gül; Ozansoy, Mehmet; Kılıç, Ülkan; Togay, Sine Özmen; Keskin, İlknur; Özdemir, Ekrem Musa; Günal, Mehmet Yalçın (2021)Objective: Treatment of inflammatory bowel disease (IBD) usually involves medical therapy. For this reason, it is recommended to seek alternative treatment methods such as nutritional therapy. The aim of the study is to ... -
The effect of rifampicin on the neuronal cell survival in primary cortical neuron culture after laser axotomy
Ozansoy, Mehmet; Coşkun, Ebru; Ozansoy, Muzaffer Beyza; Çankaya, Şeyda; Günal, Mehmet Yalçın; Bayraktaroğlu, Zübeyir; Hanoğlu, Lütfü (Alanya Alaaddin Keykubat Üniversitesi, 2019)Aim: Neurodegeneration caused by the axonal injury is a widely seen phenomenon in spinal cord and traumatic brain injuries. Due to the disintegration of the synaptic connection neurotrophic factors could not be transported ... -
The effects of carvacrol on oxidative stress parameters and adoptosis process via TRPA1 channels in neuroblastoma cells
Günal, Mehmet Yalçın; Övey, İshak Suat (Polskie Towarzystwo Farmaceutyczne, 2019)Objectives: This study is a preliminary study to investigate the effects of carvacrol (CRV) obtained from thyme on the apoptosis process in neuroblastoma cells. Methods: In this study, seven groups were designed as control, ... -
The effects of topical liposomal resveratrol on incisional and excisional wound healing process
Günal, Mehmet Yalçın; Ayla, Şule; Bedri, Nejda; Beker, Mustafa Çağlar; Çağlayan, Ahmet Burak; Aslan, İsmail; Kılıç, Ülkan (2019)Background and Design: The objective of this study was to investigate the wound healing activity of different concentrations of liposomal trans-resveratrol formulations on incisional and excisional wounds in rats. Materials ... -
Evaluation of the bilateral cardiac afferent distribution at the spinal and vagal ganglia by retrograde labeling
Çağlar, Tuba Akgül; Durdu, Zeynep Begüm; Turhan, Mehmet Uğurcan; Günal, Mehmet Yalçın; Aydın, M. S.; Özturk, Gürkan; Çağavi, Esra (Elsevier, 2021)The identity of sensory neurons innervating the heart tissue and the extent of information reported to the brain via these neurons are poorly understood. In order to evaluate the multidimensional distribution and abundance ... -
Experimental data of labeling the heart and cardiac cultures with a retrograde tracer in vitro and in vivo
Çağlar, Tuba Akgül; Günal, Mehmet Yalçın; Turhan, Mehmet Uğurcan; Öztürk, Gürkan; Çağavi, Esra (2021)Retrograde dyes are often used in basic research to investigate neuronal innervations of an organ. This article describes the experimental data on the application of retrograde dyes on the mouse heart in vivo and on the ... -
In vivo wound-healing and in vitro antibacterial and antioxidant properties of Carduus adpressus extract
Şakul, Ayşe Arzu; Ayla, Şule; Okur, Mehmet Evren; Karadağ, Ayşe Esra; Daylan, Benay; Güzel, Elif; Özdemir, Ekrem Musa; Günal, Mehmet Yalçın (2023)Carduus adpressus has been used for its anti-hair loss effect in traditional folk medicine. The plant species is mainly distributed in Türkiye, Bulgaria, and the Western Caucasus. The studies on this specific plant in the ... -
Investigation of the effect of adalimumab on experimental brain injury in mice
Günal, Mehmet Yalçın; Çankaya, Seyda; Tönük, Şükrü Burak; Özdemir, Ekrem Musa; Şakul, Ayşe Arzu Sayın (Alanya Alaaddin Keykubat Üniversitesi, 2019)Aim: We aimed to investigate the neuroprotective role of adalimumab based on the hypothesis that "TNF-alpha inhibitor adalimumab may affect inflammationrelated neuronal injury due to its anti-inflammatory effect". Methods: ... -
Prunus spinosa L. meyvelerinin deneysel yara iyileşmesi üzerine etkileri
Ayla, Şule; Günal, Mehmet Yalçın; Şakul, Ayşe Arzu Sayın; Biçeroğlu, Özge; Özdemir, Ekrem Musa; Okur, Mehmet Evren; Bilgiç, Bülent Emre (2017)Farelerde oluşturduğumuz deneysel yara modellerinde, Prunus Spinosa L. metanollü meyve ekstresini kullanarak, bu ekstrenin yara iyileşmesindeki etkisini araştırdık. Otuz iki adet C57/Black fare ile 4 deney grubu oluşturuldu. ... -
Role of erythropoietin and its receptor in the development of endometriosis in rats
Günal, Mehmet Yalçın; Ozansoy, Mehmet; Kılıç, Ülkan; Keskin, İlknur; Özdemir, Ekrem Musa; Aslan, İsmail; Kılıç, Ertuğrul (2019)Objective: Besides its hematopoietic function, erythropoietin (EPO) may protect tissues from degenerative disorders. As such, EPO and its receptors were revealed in nonhematopoietic cells, including stromal and endometrial ... -
Squalene attenuates the oxidative stress and activates AKT/mTOR pathway against cisplatin-induced kidney damage in mice
Sakul, Arzu; Ozansoy, Mehmet; Elibol, Birsen; Ayla, Şule; Günal, Mehmet Yalçın; Yozgat, Yasemin; Kılıç, Ülkan (2019)The clinical use of cisplatin, which is a first-line anticancer agent, is highly restricted due to its adverse effects on kidneys that lead to nephrotoxicity. Therefore, some potential reno-protective substances have been ... -
Tıp Fakültesi ve Turizm Fakültesi öğrencilerinin sağlık turizmi hakkındaki farkındalık düzeyleri
Dağlı, Mehmet (Alanya Alaaddin Keykubat Üniversitesi, 2021)Modern anlamda sağlık turizmi, son dönemlerde dünya genelinde yerini ve önemini belirginleştiren bir kavram olarak karşımıza çıkmaktadır. Kalkınma ve/veya gelişme hedefi doğrultusunda arayışı olan ülkeler sektörün getirisinin ... -
Wound Healing Activity of Arum Maculatum
Arzu Sakul, Ayşe; Okur, Mehmet Evren; Ayla, Şule; Daylan, Benay; Karadağ, Ayşe Esra; Batur, Şebnem; Özdemir, Ekrem Musa; Altınalan, Ebrar; Günal, Mehmet Yalçın (2023)Objective: In this study, the antioxidant properties of Arum maculatum plant were evaluated. This study reported for the first time the wound healing activity of the methanol extract of A. maculatum fruits. This study aimed ... -
Wound healing effects of methanol extract of Laurocerasus officinalis roem
Ayla, Şule; Okur, Mehmet Evren; Günal, Mehmet Yalçın; Özdemir, Ekrem Musa; Polat, Derya Çiçek; Yoltaş, Ayşegül; Biçeroğlu, Özge; Karahüseyinoğlu, Serçin (Taylor & Francis Ltd, 2019)Laurocerasus officinalis Roem. (syn: Prunus laurocerasus L.) is a member of Rosaceae family. We investigated the antimicrobial and antioxidant activity of L. officinalis Roem in wound healing both in vivo and in vitro using ...
