Yazar "Ballar Kırmızıbayrak, Petek" için listeleme
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Design, synthesis, biological evaluation and molecular docking of novel molecules to PARP-1 enzyme
Tok, Fatih; Kaymakçıoğlu Bedia; İlhan, Recep; Yılmaz, Sinem; Ballar Kırmızıbayrak, Petek; Taşkın Tok, Tuğba (TUBITAK, 2019)Poly (ADP-ribose) polymerase (PARP) enzyme catalyzes the transfer of ADP-ribose into target proteins. Therefore, PARP is responsible for DNA repair, cell proliferation, and cell death. In this study, potential PARP enzyme ... -
The role of cycloastragenol at the intersection of NRF2/ARE, telomerase, and proteasome activity
Aging is well-characterized by the gradual decline of cellular functionality. As redox balance, proteostasis, and telomerase systems have been found to be associated with aging and age-related diseases, targeting these ...