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Design, synthesis, biological evaluation and molecular docking of novel molecules to PARP-1 enzyme

Tok, Fatih; Kaymakçıoğlu Bedia; İlhan, Recep; Yılmaz, Sinem; Ballar Kırmızıbayrak, Petek; Taşkın Tok, Tuğba (TUBITAK, 2019)

Poly (ADP-ribose) polymerase (PARP) enzyme catalyzes the transfer of ADP-ribose into target proteins. Therefore, PARP is responsible for DNA repair, cell proliferation, and cell death. In this study, potential PARP enzyme ...