Yazar "Çankaya, Şeyda" için listeleme
-
The association of non-motor symptoms with motorsymptoms in parkinson’s disease
Çankaya, Şeyda (2021)Aim: Idiopathic Parkinson’s disease (IPD) is the second most common progressive neurodegenerative disorder and well known with typical motor impairment. Besides motor symptoms, non-motor symptoms (NMS) occur very frequently ... -
Combined metabolic activators improve cognitive functions in Alzheimer’s disease patients: a randomised, double-blinded, placebo-controlled phase-II trial
Yuluğ, Burak; Altay, Özlem; Li, Xiangyu; Hanoğlu, Lütfü; Çankaya, Şeyda; Lam, Simon; Velioğlu, Halil Aziz; Yang, Hong; Coşkun, Ebru; İdil, Ezgi; Nogaylar, Rahim; Özşimşek, Ahmet; Bayram, Cemil; Bolat, İsmail; Öner, Sena; Tozlu, Özlem Özdemir; Arslan, Mehmet Enes; Hacımüftüoğlu, Ahmet; Yıldırım, Serkan; Arif, Muhammad; Shoaie, Saeed; Zhang, Cheng; Nielsen, Jens; Turkez, Hasan; Boren, Jan; Uhlen, Mathias; Mardinoğlu, Adil (2023)Abstract Background Alzheimer’s disease (AD) is associated with metabolic abnormalities linked to critical elements of neurodegeneration. We recently administered combined metabolic activators (CMA) to the AD rat model ... -
A different view on the pathophysiology of Parkinson's disease: a descendent neurochemical hypothesis?
Yuluğ, Burak; Ozansoy, Mehmet; Çankaya, Şeyda (Wolters Kluwer Medknow Publications, 2019)[No abstract available] -
The effect of Resveratrol on sphingosine-1 and Oxidative/ Nitrosative stress in an experimental heart ischemia reperfusion model
Avnioğlu, Seda; Güngör, Meltem; Kurutaş, Ergül; Öztürk, Ünal; Demirhan, İlter; Bakaris, Sevgi; Velioğlu, Halil Aziz; Çankaya, Şeyda; Yuluğ, Burak (2022)Objectives: Resveratrol (RSV) is a natural polyphenolic compound showing significant antioxidant effects. In this study, we aimed to investigate the effects of resveratrol on the sphingosine-1-phosphate (S1P) and oxidative ... -
The effect of rifampicin on the neuronal cell survival in primary cortical neuron culture after laser axotomy
Ozansoy, Mehmet; Coşkun, Ebru; Ozansoy, Muzaffer Beyza; Çankaya, Şeyda; Günal, Mehmet Yalçın; Bayraktaroğlu, Zübeyir; Hanoğlu, Lütfü (Alanya Alaaddin Keykubat Üniversitesi, 2019)Aim: Neurodegeneration caused by the axonal injury is a widely seen phenomenon in spinal cord and traumatic brain injuries. Due to the disintegration of the synaptic connection neurotrophic factors could not be transported ... -
Minocycline increases in-vitro cortical neuronal cell survival after laser induced axotomy
Yuluğ, Burak; Ozansoy, Mehmet; Alökten, Merve; Ozansoy, Muzaffer; Çankaya, Şeyda; Hanoğlu, Lütfü; Kılıç, Ertuğrul (Bentham Science Publ Ltd, 2020)Background: Antibiotic therapies targeting multiple regenerative mechanisms have the potential for neuroprotective effects, but the diversity of experimental strategies and analyses of non-standardised therapeutic trials ... -
Paracetamol alters empathy scores in healthy and headache subjects: Functional MRI correlates
Çankaya, Şeyda; Öktem, Ece Özdemir; Saatçi, Özlem; Vehoğlu, Halil Aziz; Uygur, Abdullah Burak; Özşimşeka, Ahmet; Yuluğ, Burak (Elsevier Sci Ltd, 2020)Introduction: Although previous evidence suggest that paracetamol decreases psychological reactivity in healthy subjects, there is still no confirmed correlation between the empathy scores and brain activity in healthy and ... -
A rare entity of acquired idiopathic generalised anhidrosis which has been successfully treated with pulse steroid therapy: Does the histopathology predict the treatment response?
Öktem, Ece Özdemir; Çankaya, Şeyda; Uykur, Abdullah Burak; Erdem, Nazan Şimşek; Yuluğ, Burak (Ifjusagi Lap-es Konyvkiado Vallalat, 2020)Acquired idiopathic generalised anhidrosis is an uncommon sweating disorder characterized by loss of sweating in the absence of any neurologic, metabolic or sweat gland abnormalities. Although some possible immunological ... -
The relationship between the changes in inflammatory parameters and response to treatment in major depression patients starting antidepressant treatment
Uygur, Abdullah Burak; Çankaya, Şeyda (2021)Aim: Changes in inflammatory parameters such as cytokines, stress hormones and C reactive protein that occur in depression, are important in understanding the pathophysiology of depression and developing new treatment ... -
The therapeutic role of minocycline in Parkinson's disease
Çankaya, Şeyda; Çankaya, Barış; Kılıç, Ülkan; Kılıç, Ertuğrul; Yuluğ, Burak (Bioexcel Publishing LTD, 2019)Minocycline, a semisynthetic tetracycline-derived antibiotic, has been shown to exert anti-apoptotic, anti-inflammatory, and antioxidant effects. Furthermore, there is rapidly growing evidence suggesting that minocycline ... -
Topological network mechanisms of clinical response to antidepressant treatment in drug-naive major depressive disorder
Uykur, Abdullah Burak; Yıldız, Sultan; Velioğlu, Halil Aziz; Özşimşek, Ahmet; Öktem, Ece Özdemir; Bayraktaroğlu, Zübeyir; Ergün, Tarkan; Lakadamyalı, Hatice; Hanoğlu, Lütfi; Hanoğlu, Lütfi; Çankaya, Şeyda; Saatçi, Özlem; Yuluğ, Burak (Churchill Livingstone, 2021)Aim: There is rapidly increasing evidence that remission of MDD is associated with substantial changes in functional brain connectivity. These New data have provided a holistic view on the mechanism of antidepressants on ... -
Translational perspective: is cinnamon a suitable agent for cognitive impairment and Alzheimer's disease associated with brain trauma
Yuluğ, Burak; Çankaya, Şeyda (Wolters Kluwer Medknow Publications, 2019)[No abstract available]
